This package provides a novel algorithm that solves the P-value calculation problem given the score based on a Postion Weight Matrices (PWMs), or the reverse problem: finding the score give the desired P-value. This package is an interface to code originally made available by Helene Touzet and Jean-Stephane Varre, 2007, Algorithms Mol Biol:2, 15.
The original code is taken from http://bioinfo.lifl.fr/TFM/TFMpvalue/TFM-Pvalue.tar.gz, retrived 26/03/2014.
The algorithm is described in Touzet, H., and Varre, J.-S. (2007). Efficient and accurate P-value computation for Position Weight Matrices. Algorithms Mol Biol 2, 15.