distribution: distribution

In TSDT: Treatment-Specific Subgroup Detection Tool

distribution

Description

Returns the distribution of values used to compute TSDT summary statistics.

Usage

distribution(object, statistic, subgroup = NULL, subsub = NULL)

Arguments

object	An object of class TSDT
statistic	The desired statistic distribution
subgroup	The desired subgroup
subsub	A subset of the subgroup

Details

This function returns the distribution of all values used to compute summary statistics for superior subgroups identified by the TSDT algorithm. The summary statistics returned for a TSDT object include the mean subgroup size, mean response value, and median value of the scoring function. These statistics reported seperately for in-bag and out-of-bag data sets, and also stratified by treatment arm. This function can also provide the distribution of all cutpoints for a numeric splitting variable in a subgroup definition.

Value

A vector containing the observed values for the specified subgroup

See Also

TSDT, summary-methods

Examples

set.seed(0)
N <- 200
continuous_response = runif( min = 0, max = 20, n = N )
trt <- sample( c('Control','Experimental'), size = N, prob = c(0.4,0.6),
               replace = TRUE )
X1 <- runif( N, min = 0, max = 1 )
X2 <- runif( N, min = 0, max = 1 )
X3 <- sample( c(0,1), size = N, prob = c(0.2,0.8), replace = TRUE )
X4 <- sample( c('A','B','C'), size = N, prob = c(0.6,0.3,0.1), replace = TRUE )
covariates <- data.frame( X1 )
covariates$X2 <- X2
covariates$X3 <- factor( X3 )
covariates$X4 <- factor( X4 )

## Create a TSDT object
ex1 <- TSDT( response = continuous_response,
            trt = trt, trt_control = 'Control',
            covariates = covariates[,1:4],
            inbag_score_margin = 0,
            desirable_response = "increasing",
            oob_score_margin = 0,
            min_subgroup_n_control = 5,
            min_subgroup_n_trt = 5,
            n_sample = 5 )

## Show summary statistics
summary( ex1 )

## Get the number of subjects in each superior in-bag subgroup
distribution( ex1, statistic = 'Inbag_Subgroup_Size' )

## Get the vector of subgroup sample sizes for a particular subgroup
distribution( ex1, statistic = 'Inbag_Subgroup_Size',
              subgroup = 'X1<xxxxx & X1>=xxxxx' )

## Get the observed cutpoints for the numeric splitting variables in a subgroup
distribution( ex1, statistic = 'Cutpoints', subgroup = 'X1<xxxxx & X1>=xxxxx' )

## If the subgroup definition has more than one numeric splitting variable you
## can retrieve the numeric cutpoints for the splitting variables individually
distribution( ex1, statistic = 'Cutpoints', subgroup = 'X1<xxxxx & X1>=xxxxx',
              subsub = 'X1<xxxxx' )
distribution( ex1, statistic = 'Cutpoints', subgroup = 'X1<xxxxx & X1>=xxxxx',
              subsub = 'X1>=xxxxx' )

## Valid statistic names come from the column names in the summary output. If
## you are uncertain what the possible statistic values could be, you can pass
## any arbitrary string as the statistic and an error message is returned
## listing valid statistic values.
## Not run: 
distribution( ex1, statistic = 'Invalid_Statistic' )

## End(Not run)

TSDT documentation built on April 7, 2022, 1:07 a.m.