get_suggested_subgroup: get_suggested_subgroup

In TSDT: Treatment-Specific Subgroup Detection Tool

get_suggested_subgroup

Description

Get a string definition of the suggested subgroup definition.

Usage

get_suggested_subgroup(anonymized_subgroup, suggested_cutoff, anon = "xxxxx")

Arguments

anonymized_subgroup	A string containing the the anonymized subgroup.
suggested_cutoff	A string containing the suggested cutoff.
anon	The anonymization string. By default this is 'xxxxx'.

Details

Subgroups are reported in an anonymized fashion – e.g. a subgroup defined on a variable X1 could be reported as X1<xxxxx, 'xxxxx' is a string used to represent an exact numeric cutoff. For each anonymized subgroup, the distribution of exact numeric cutpoints is retained across all bootrstrapped samples. TSDT then provides a suggested cutoff got each anonymized subgroup. By default, this suggested cutoff is the median of the observed cutpoints. Note that this anonymization applies only to numeric splitting variables. Categorical splitting variables are not anonymized.

Examples

set.seed(0)
N <- 200
continuous_response = runif( min = 0, max = 20, n = N )
trt <- sample( c('Control','Experimental'), size = N, prob = c(0.4,0.6), replace = TRUE )
X1 <- runif( N, min = 0, max = 1 )
X2 <- runif( N, min = 0, max = 1 )
X3 <- sample( c(0,1), size = N, prob = c(0.2,0.8), replace = TRUE )
X4 <- sample( c('A','B','C'), size = N, prob = c(0.6,0.3,0.1), replace = TRUE )
covariates <- data.frame( X1 )
covariates$X2 <- X2
covariates$X3 <- factor( X3 )
covariates$X4 <- factor( X4 )

## Create a TSDT object
ex1 <- TSDT( response = continuous_response,
             trt = trt, trt_control = 'Control',
             covariates = covariates[,1:4],
             inbag_score_margin = 0,
             desirable_response = "increasing",
             oob_score_margin = 0,
             min_subgroup_n_control = 10,
             min_subgroup_n_trt = 20,
             maxdepth = 2,
             rootcompete = 2 )

## Show summary statistics
summary( ex1 )

## Get the anonymized subgroup defined on X1
anonymized_subgroup <- as.character( ex1@superior_subgroups$Subgroup[2] )

## Get the suggested cutoff for this subgroup
suggested_cutoff <- as.character( ex1@superior_subgroups$Suggested_Cutoff[2] )

## Get the suggested subgroup
get_suggested_subgroup( anonymized_subgroup = anonymized_subgroup,
                        suggested_cutoff = suggested_cutoff )

TSDT documentation built on April 7, 2022, 1:07 a.m.