ThreeArmedTrials: Design and Analysis of Clinical Non-Inferiority or Superiority Trials with Active and Placebo Control

Design and analyze three-arm non-inferiority or superiority trials which follow a gold-standard design, i.e. trials with an experimental treatment, an active, and a placebo control.

Author
Tobias Muetze [aut, cre], Tim Friede [ctb]
Date of publication
2016-05-17 21:13:35
Maintainer
Tobias Muetze <tobias.muetze@outlook.com>
License
GPL (>= 2)
Version
1.0-0
URLs

View on CRAN

Man pages

binary_likelihood_rest
binary_likelihood_rest
calc_power_ret
calc_power_ret
calc_power_ret.binary
calc_power_ret.binary
calc_power_ret.default
power_ret.default
calc_power_ret.exponential
calc_power_ret.exponential
calc_power_ret.negbin
calc_power_ret.negbin
calc_power_ret.poisson
calc_power_ret.poisson
calc_test_ret
calc_test_ret
calc_test_ret.default
test_ret.default
calc_test_ret.nonparametric
calc_test_ret.nonparametric
calc_test_ret.normal
calc_test_ret.normal
check_missing
check_missing
check_RET_arguments
check_RET_arguments
estimate
estimate
estimate.binary
estimate.binary
estimate.default
estimate.default
estimate.exponential
estimate.exponential
estimate.negbin
estimate.negbin
estimate.nonparametric
estimate.nonparametric
estimate.normal
estimate.normal
estimate.poisson
estimate.poisson
GElesions
Total number of new galodinium-enhancing lesions.
grad_poisson_likelihood
grad_poisson_likelihood
init_power
init_power
init_test
init_test
is.naturalnumber
is.naturalnumber
limit_RML_binary
limit_RML_binary
limit_RML_poisson
limit_RML_poisson
loglikelihood_binary
loglikelihood_binary
negbin_likelihood
negbin_likelihood
opt_alloc_RET
Optimal sample size for three-arm trials when analyzed with a...
poisson_likelihood
poisson_likelihood
power_RET
Power related calcuations for three-arm clinical trials
power.taNegbin.test
Power related calcuations for three-armed clinical trials...
remission
Remission in clinical trial in patients with depression.
seizures
Number of seizures per patient.
T2lesions
Number of new and enlarging T2 lesions per patient.
taNegBin.OptAllocation
Optimal sample size for three-armed clinical trials with...
taNegbin.test
Statistical test for three-armed clinical trials with...
test_RET
Wald-type test for three-arm trials
ThreeArmedTrials
Design and Analysis of Three-armed Clinical Non-Inferiority...

Files in this package

ThreeArmedTrials
ThreeArmedTrials/inst
ThreeArmedTrials/inst/doc
ThreeArmedTrials/inst/doc/ThreeArmedTrials.R
ThreeArmedTrials/inst/doc/ThreeArmedTrials.html
ThreeArmedTrials/inst/doc/ThreeArmedTrials.Rmd
ThreeArmedTrials/tests
ThreeArmedTrials/tests/testthat.R
ThreeArmedTrials/tests/testthat
ThreeArmedTrials/tests/testthat/test-normal.R
ThreeArmedTrials/tests/testthat/test-exponential.R
ThreeArmedTrials/tests/testthat/test-nonparametric.R
ThreeArmedTrials/tests/testthat/test-NegBin.R
ThreeArmedTrials/tests/testthat/test-binary.R
ThreeArmedTrials/tests/testthat/test-general.R
ThreeArmedTrials/tests/testthat/test-poisson.R
ThreeArmedTrials/src
ThreeArmedTrials/src/newton_Shape.c
ThreeArmedTrials/NAMESPACE
ThreeArmedTrials/NEWS.md
ThreeArmedTrials/data
ThreeArmedTrials/data/GElesions.rda
ThreeArmedTrials/data/remission.rda
ThreeArmedTrials/data/seizures.rda
ThreeArmedTrials/data/T2lesions.rda
ThreeArmedTrials/R
ThreeArmedTrials/R/ThreeArmedTrials.R
ThreeArmedTrials/R/nonparametric.R
ThreeArmedTrials/R/waldtype_test.R
ThreeArmedTrials/R/generic_functions.R
ThreeArmedTrials/R/power.taNegbin.test.R
ThreeArmedTrials/R/initialize.R
ThreeArmedTrials/R/utilities.R
ThreeArmedTrials/R/negativebinomial.R
ThreeArmedTrials/R/data.R
ThreeArmedTrials/R/binary.R
ThreeArmedTrials/R/default_methods.R
ThreeArmedTrials/R/normal.R
ThreeArmedTrials/R/taNegbinVarEst.R
ThreeArmedTrials/R/taNegBin.OptAllocation.R
ThreeArmedTrials/R/waldtype_power.R
ThreeArmedTrials/R/exponential.R
ThreeArmedTrials/R/likelihoods.R
ThreeArmedTrials/R/estimate.R
ThreeArmedTrials/R/RML_limit.R
ThreeArmedTrials/R/taNegbin.test.R
ThreeArmedTrials/R/waldtype_optAlloc.R
ThreeArmedTrials/R/poisson.R
ThreeArmedTrials/vignettes
ThreeArmedTrials/vignettes/ThreeArmedTrials.Rmd
ThreeArmedTrials/README.md
ThreeArmedTrials/MD5
ThreeArmedTrials/build
ThreeArmedTrials/build/vignette.rds
ThreeArmedTrials/DESCRIPTION
ThreeArmedTrials/man
ThreeArmedTrials/man/estimate.default.Rd
ThreeArmedTrials/man/negbin_likelihood.Rd
ThreeArmedTrials/man/estimate.exponential.Rd
ThreeArmedTrials/man/test_RET.Rd
ThreeArmedTrials/man/calc_power_ret.negbin.Rd
ThreeArmedTrials/man/limit_RML_poisson.Rd
ThreeArmedTrials/man/remission.Rd
ThreeArmedTrials/man/grad_poisson_likelihood.Rd
ThreeArmedTrials/man/T2lesions.Rd
ThreeArmedTrials/man/estimate.poisson.Rd
ThreeArmedTrials/man/estimate.negbin.Rd
ThreeArmedTrials/man/seizures.Rd
ThreeArmedTrials/man/limit_RML_binary.Rd
ThreeArmedTrials/man/is.naturalnumber.Rd
ThreeArmedTrials/man/power_RET.Rd
ThreeArmedTrials/man/power.taNegbin.test.Rd
ThreeArmedTrials/man/poisson_likelihood.Rd
ThreeArmedTrials/man/calc_power_ret.poisson.Rd
ThreeArmedTrials/man/loglikelihood_binary.Rd
ThreeArmedTrials/man/GElesions.Rd
ThreeArmedTrials/man/calc_power_ret.exponential.Rd
ThreeArmedTrials/man/calc_test_ret.Rd
ThreeArmedTrials/man/calc_test_ret.nonparametric.Rd
ThreeArmedTrials/man/check_missing.Rd
ThreeArmedTrials/man/ThreeArmedTrials.Rd
ThreeArmedTrials/man/init_power.Rd
ThreeArmedTrials/man/estimate.binary.Rd
ThreeArmedTrials/man/estimate.Rd
ThreeArmedTrials/man/estimate.nonparametric.Rd
ThreeArmedTrials/man/calc_test_ret.default.Rd
ThreeArmedTrials/man/calc_test_ret.normal.Rd
ThreeArmedTrials/man/taNegbin.test.Rd
ThreeArmedTrials/man/taNegBin.OptAllocation.Rd
ThreeArmedTrials/man/calc_power_ret.Rd
ThreeArmedTrials/man/estimate.normal.Rd
ThreeArmedTrials/man/init_test.Rd
ThreeArmedTrials/man/binary_likelihood_rest.Rd
ThreeArmedTrials/man/calc_power_ret.default.Rd
ThreeArmedTrials/man/opt_alloc_RET.Rd
ThreeArmedTrials/man/check_RET_arguments.Rd
ThreeArmedTrials/man/calc_power_ret.binary.Rd