Man pages for TrialSimulator
Clinical Trial Simulator

armDefine an Arm
ArmsClass of Arm
calendarTimeTriggering condition by calendar time
controllerDefine a Controller
ControllersClass of Controller
CorrelatedPfsAndOs3Generate PFS and OS using the three-states model
CorrelatedPfsAndOs4Generate PFS, OS and objective response using the four-states...
default_actiondefault action function for dry run of a trial
doNothingAn action function that does nothing
DynamicRNGFunctionA wrapper of random number generator.
endpointDefine endpoints
EndpointsClass of Endpoint
enrollmentTriggering condition by number of randomized patients
eventNumberTriggering condition by number of events or observations of...
fitCoxphFit Cox proportional hazard ratio model
fitFarringtonManningFarrington-Manning test for rate difference
fitLinearFit linear regression model
fitLogisticFit logistic regression model
fitLogrankCarry out log rank test
getAdaptiveDesignOutputGet simulation output in the vignette adaptiveDesign.Rmd
getFixedDesignOutputGet simulation output in the vignette fixedDesign.Rmd
GraphicalTestingClass of GraphicalTesting
GroupSequentialTestClass of GroupSequentialTest
listenerDefine a Listener
ListenersClass of Listener
milestoneDefine a Milestone of a Trial
MilestonesClass of Milestones
PiecewiseConstantExponentialRNGGenerate time-to-event endpoint from piecewise constant...
plot.milestone_time_summaryPlot Triggering Time of Milestones in Simulated Trials
plot.three_state_modelPlot result of three-state ill-death model
rconstGenerate constant variable
solveMixtureExponentialDistributionSolve parameters in a mixture exponential distribution
solveThreeStateModelSolve parameters in a three-state ill-death model
StaggeredRecruiterGenerate enrollment time from piecewise constant uniform...
summarizeDataFrameSummarize A Data Frame
summarizeMilestoneTimeSummary of Milestone Time from Simulated Trials
trialDefine a Trial
TrialsClass of Trial
weibullDropoutCalculate Parameters of Weibull Distribution as a Dropout...
TrialSimulator documentation built on Sept. 9, 2025, 5:26 p.m.