adpss: Design and Analysis of Locally or Globally Efficient Adaptive Designs

Provides the functions for planning and conducting a clinical trial with adaptive sample size determination. Maximal statistical efficiency will be exploited even when dramatic or multiple adaptations are made. Such a trial consists of adaptive determination of sample size at an interim analysis and implementation of frequentist statistical test at the interim and final analysis with a prefixed significance level. The required assumptions for the stage-wise test statistics are independent and stationary increments and normality. Predetermination of adaptation rule is not required.

Package details

AuthorKosuke Kashiwabara [aut, cre]
MaintainerKosuke Kashiwabara <[email protected]>
LicenseGPL (>= 2)
Version0.1.1
URL https://github.com/ca4wa/R-adpss
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("adpss")

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adpss documentation built on Sept. 21, 2018, 6:23 p.m.