setup_cppglobal: Setup Global Calibrated Power Prior Design Object

In basksim: Simulation-Based Calculation of Basket Trial Operating Characteristics

Setup Global Calibrated Power Prior Design Object

Description

Setup Global Calibrated Power Prior Design Object

Usage

setup_cppglobal(k, p0, shape1 = 1, shape2 = 1)

Arguments

k	The number of baskets.
p0	A common probability under the null hypothesis.
shape1	First common shape parameter of the beta prior.
shape2	Second common shape parameter of the beta prior.

Details

The class cppglobal implements a version of the power prior design, in which the amount of information that is shared between baskets is determined by the Kolmogorov-Smirnov test statistic between basekts and a function based on response rate differences that quantifies the overall heterogeneity.

Value

An S3 object of class cppglobal

References

Baumann, L., Sauer, L., & Kieser, M. (2024). A basket trial design based on power priors. arXiv:2309.06988.

Examples

design_cppglobal <- setup_cppglobal(k = 3, p0 = 0.2)

basksim documentation built on June 24, 2024, 5:13 p.m.