miRNA: miRNA transfection data for miR1 and miR124 target genes

In bgmm: Gaussian Mixture Modeling Algorithms and the Belief-Based Mixture Modeling

Description

miRNA transfection data (Lim et al., 2005) and knowledge from computational miRNA target predictions.

Usage

data(miRNA)

Format

miR1Data vector: 117, miR124Data vector: 117, miRNABeliefs matrix of example certainty: 26 x 2, miRNAClass vector: 117

Details

miR1Data Log2 expression ratios of miR1 transfection versus wild type, for 117 genes. miR124Data Log2 expression ratios of miR124 transfection versus wild type, for 117 genes. miRNABeliefs Gives the certainty (belief/plausibility) for each out of 26 example miRNA targets to belong to their cluster. miRNAClass Gives the true cluster for each gene. Cluster 1 corresponds to the experimentally verified targets of miR1. Cluster 2 corresponds to the targets of miR124.

Author(s)

Ewa Szczurek

References

Lim, L. P., Lau, N. C., Garrett-Engele, P., Grimson, A., Schelter, J. M., Castle, J., Bartel, D. P., Linsley, P. S., and Johnson, J. M. (2005). Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature, 433(7027).

See Also

Ste12,CellCycle

Examples

library(bgmm)
data(miRNA)
print(miR1Data)
print(miR124Data)
print(miRNABeliefs)
print(miRNAClass)

bgmm documentation built on Oct. 10, 2021, 5:07 p.m.