Implements a method for identifying and removing the cell-cycle effect from scRNA-Seq data. The description of the method is in Barron M. and Li J. (2016) <doi:10.1038/srep33892>. Identifying and removing the cell-cycle effect from single-cell RNA-Sequencing data. Submitted. Different from previous methods, ccRemover implements a mechanism that formally tests whether a component is cell-cycle related or not, and thus while it often thoroughly removes the cell-cycle effect, it preserves other features/signals of interest in the data.
Package details |
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Author | Jun Li [aut, cre], Martin Barron [aut] |
Maintainer | Jun Li <jun.li@nd.edu> |
License | GPL-3 |
Version | 1.0.4 |
Package repository | View on CRAN |
Installation |
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