Description Usage Arguments Value
This function is only used internally inside ccRemover. The function calcualtes the average load difference on the cell-cycle and control genes. Bootstrap resampling is then used to provide a score for each component. Please see the original manuscript for the mathematical details.
1 | bootstrap_diff(xy, xn, nboot = 200, bar = TRUE)
|
xy |
The data for the genes which are annotated to the cell-cycle, i.e.
those genes for which "if_cc" is |
xn |
The data for the genes which are not annotated to the cell-cycle,
control genes, genes for which "if_cc" is |
nboot |
The number of bootstrap repititions to be carried out on each iteration to determine the significance of each component. |
bar |
Whether to display a progress bar or not. The progress bar will
not work in R-markdown enviornments so this option may be turned off. The
default value is |
A data frame containing the loadings for each component on the cell-cycle and control genes as well as the difference between the loadings and the bootstrapped statistic for each loading.
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