catie_sim: Simulated data, loosely based on the Clinical Antipsychotic...
In confoundr: Diagnostics for Confounding of Time-Varying and Other Joint Exposures

Description Usage Format References

1430 completely hypothetical persons with schizophrenia randomized to one of five antipsychotics and followed for up to 18 months. Note that the simulation did not build in sequential randomization, as was done in the trial.

1	data(catie_sim)

A dataframe with 8,632 rows and 62 variables:

CATIEID: person id
time: month of study visit (0, 1, 3, 6, 9, 12, 15, 18)
td: tardive diskinesia stratum
zprcort: ziprasidone cohort stratum
race: 1:white, 2:black, 3:other
age.grp: 1:18-24, 2:25-34, 3:45-44, 4:45-54, 5:55-67
educ.bin: high school graduate
site.ro: study site, research only
site.sh: study site, state mental health
site.uc: study site, university center
site.va: study site, veterans affairs
treat.grp: antipsychotic 1:ola, 2:que, 3:ris, 4:per, 5:zip
cs14: drug use scale
cs16: clinical global impressions (CGI) severity scale
calg1: calgary depression scale
weight: in lbs
epsmean: Simpson-Agnes extrapyramidal symptoms
qoltot: quality of life total score
pansstotal: positive and negative syndrome scale (PANSS)
phase.change.vis: switch to new antipsychotic
white: race dummy variable, white
black: race dummy variable, black
other: race dummy variable, other
age.grp.1824: age group dummy variable, 18-24 years
age.grp.2534: age group dummy variable, 25-34 years
age.grp.3544: age group dummy variable, 35-44 years
age.grp.4554: age group dummy variable, 45-54 years
age.grp.5567: age group dummy variable, 55-67 years
Bpansstotal: pansstotal at time 0
Bcs14: cs14 at time 0
Bcs16: cs16 at time 0
Bcalg1: calg1 at time 0
Bqoltot: qoltot at time 0
Chg.pansstotal: change in pansstotal
pct.gain: percent weight gain
phase.change.cum: number of switches to antipsychotic
phase.change.cum.rec: time-varying version of ever switch to antipsychotic
lead.pansstotal: pansstotal at next visit
treat.grp.ola: olanzapine arm dummy
treat.grp.que: quetiapine arm dummy
treat.grp.ris: risperidone arm dummy
treat.grp.per: perphenazine arm dummy
treat.grp.zip: ziprasidone arm dummy
studydisc: last visit (1=yes, 0 otherwise)
num.x: probability of treatment arm
den.x: probability of treatment arm given baseline covariates
wx.b: stabilized iptw for treatment arm
num.po: probability studydisc=1, given treat.grp & baseline covariates, common model
den.po: probability studydisc=1, given treat.grp & baseline and time-varying covariates, common model
num.tr: probability studydisc=1, given treat.grp & baseline covariates, treat.grp specific model
den.tr: probability studydisc=1, given treat.grp & baseline and time-varying covariates, treat.grp specific model
wpo: stabilized ipcw, from common model, not truncated
wtr: stabilized ipcw, from treat.grp specific model, not truncated
wpo: stabilized ipcw, truncated 99th tile
wtr: stabilized ipcw, from treat.grp specific model, truncated 99th tile
wpo: stabilized ipcw, from common model, truncated 95th tile
wtr: stabilized ipcw, from treat.grp specific model, truncated 95th tile
wpo: stabilized ipcw, from common model, truncated 90th tile
wtr: stabilized ipcw, from treat.grp specific model, truncated 90th tile

Lieberman JA, Stroup TS, McEvoy JP, Swartz MS, Rosenheck RA, Perkins DO, Keefe RS, Davis SM, Davis CE, Lebowitz BD, Severe J, Hsiao JK; Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) Investigators. Effectiveness of antipsychotic drugs in patients with chronic schizophrenia. N Engl J Med. 2005 Sep 22;353(12):1209-23. Epub 2005 Sep 19. Erratum in: N Engl J Med. 2010 Sep 9;363(11):1092-3. PubMed PMID: 16172203.

confoundr documentation built on Sept. 20, 2019, 9:03 a.m.