Using a computationally efficient method, the package can be used to find the corrected coverage estimate of a credible set of putative causal variants from Bayesian genetic fine-mapping. The package can also be used to obtain a corrected credible set if required; that is, the smallest set of variants required such that the corrected coverage estimate of the resultant credible set is within some user defined accuracy of the desired coverage. Maller et al. (2012) <doi:10.1038/ng.2435>, Wakefield (2009) <doi:10.1002/gepi.20359>, Fortune and Wallace (2018) <doi:10.1093/bioinformatics/bty898>.
Package details |
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Author | Anna Hutchinson [aut, cre], Chris Wallace [aut], Kevin Kunzmann [ctb] |
Maintainer | Anna Hutchinson <anna.hutchinson@mrc-bsu.cam.ac.uk> |
License | MIT + file LICENSE |
Version | 1.2.1 |
URL | https://annahutch.github.io/corrcoverage |
Package repository | View on CRAN |
Installation |
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