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#' Significance test which produces p-values and confidence intervals for each
#' pair of input features.
#'
#' @param mat Input matrix of size \code{NxF},
#' with \code{N} rows that represent samples
#' and \code{F} columns that represent features.
#' @param \dots Additional arguments passed to function \code{\link{cor.test}},
#' e.g. \code{conf.level = 0.95}.
#'
#' @return Return a list containing:
#' \item{p}{Square matrix of size \code{FxF} with p-values as cells}
#' \item{lowCI}{Square matrix of size \code{FxF}, each cell represents the
#' \emph{lower part} of a confidence interval}
#' \item{uppCI}{Square matrix of size \code{FxF}, each cell represents the
#' \emph{upper part} of a confidence interval}
#'
#' @seealso Function \code{\link{cor.test}}
#'
#' @keywords p-value confidence significance
#' @export
cor.mtest = function(mat, ...) {
mat = as.matrix(mat)
n = ncol(mat)
p.mat = lowCI.mat = uppCI.mat = matrix(NA, n, n)
diag(p.mat) = 0
diag(lowCI.mat) = diag(uppCI.mat) = 1
for (i in 1:(n - 1)) {
for (j in (i + 1):n) {
tmp = cor.test(x = mat[, i], y = mat[, j], ...)
p.mat[i, j] = p.mat[j, i] = tmp$p.value
# only 'pearson' method provides confidence intervals
if (!is.null(tmp$conf.int)) {
lowCI.mat[i, j] = lowCI.mat[j, i] = tmp$conf.int[1]
uppCI.mat[i, j] = uppCI.mat[j, i] = tmp$conf.int[2]
}
}
}
colnames(p.mat) = rownames(p.mat) = colnames(mat)
colnames(lowCI.mat) = rownames(lowCI.mat) = colnames(mat)
colnames(uppCI.mat) = rownames(uppCI.mat) = colnames(mat)
list(
p = p.mat,
lowCI = lowCI.mat,
uppCI = uppCI.mat
)
}
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