Implements weighted estimation in Cox regression as proposed by Schemper, Wakounig and Heinze (Statistics in Medicine, 2009, <doi:10.1002/sim.3623>) and as described in Dunkler, Ploner, Schemper and Heinze (Journal of Statistical Software, 2018, <doi:10.18637/jss.v084.i02>). Weighted Cox regression provides unbiased average hazard ratio estimates also in case of non-proportional hazards. Approximated generalized concordance probability an effect size measure for clear-cut decisions can be obtained. The package provides options to estimate time-dependent effects conveniently by including interactions of covariates with arbitrary functions of time, with or without making use of the weighting option.
Package details |
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Author | Daniela Dunkler [aut, cre], Georg Heinze [aut], Meinhard Ploner [aut] |
Maintainer | Daniela Dunkler <daniela.dunkler@meduniwien.ac.at> |
License | GPL-3 |
Version | 4.0.3 |
URL | https://github.com/biometrician/coxphw |
Package repository | View on CRAN |
Installation |
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