Implements weighted estimation in Cox regression as proposed by Schemper, Wakounig and Heinze (Statistics in Medicine, 2009, <doi:10.1002/sim.3623>) and as described in Dunkler, Ploner, Schemper and Heinze (Journal of Statistical Software, 2018, <doi:10.18637/jss.v084.i02>). Weighted Cox regression provides unbiased average hazard ratio estimates also in case of nonproportional hazards. Approximated generalized concordance probability an effect size measure for clearcut decisions can be obtained. The package provides options to estimate timedependent effects conveniently by including interactions of covariates with arbitrary functions of time, with or without making use of the weighting option.
Package details 


Author  Daniela Dunkler [aut, cre], Georg Heinze [aut], Meinhard Ploner [aut] 
Maintainer  Daniela Dunkler <daniela.dunkler@meduniwien.ac.at> 
License  GPL3 
Version  4.0.2 
Package repository  View on CRAN 
Installation 
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