gastric: Gastric Cancer Data

In coxphw: Weighted Estimation in Cox Regression

Description

A data set of survival times of patients with locally advanced, nonresectable gastric carcinoma. The patients were either treated with chemotherapy plus radiation or chemotherapy alone.

Usage

data(gastric)

Format

A data frame with 90 observations on the following 4 variables:

id

unique patient id.

radiation

treatment of either 0 = chemotherapy alone or 1 = chemotherapy plus radiation.

time

survival time in days.

status

0 = censored or 1 = death.

Source

Stablein DM, Carter J, Novak JW. (1981) Analysis of Survival Data with Nonproportional Hazard Functions. Controlled Clinical Trials 2:149-159. OR

http://www.mayo.edu/research/documents/gastrichtml/DOC-10027680

References

Gastrointestinal Tumor Study Group. (1982) A Comparison of Combination Chemotherapy and Combined Modality Therapy for Locally Advanced Gastric Carcinoma. Cancer 49:1771-7.

Examples

data("gastric")
plot(survfit(Surv(time, status) ~ radiation, data = gastric), lty = 1:2, las = 1,
     xscale = 365.25, xlab = "time (years)", ylab = "survival distribution function")

coxphw(Surv(time, status) ~ radiation, data = gastric, template = "AHR")

Example output

Loading required package: survival
coxphw(formula = Surv(time, status) ~ radiation, data = gastric, 
    template = "AHR")

Model fitted by weighted estimation (AHR template) 

               coef  se(coef) exp(coef) lower 0.95 upper 0.95        z
radiation 0.4625051 0.2387432  1.588047  0.9945916   2.535608 1.937249
                   p
radiation 0.05271492

Wald Chi-square=3.752934 on 1df, p=0.05271492, n=90

coxphw documentation built on July 8, 2020, 6:52 p.m.