cpk: Clinical Pharmacokinetics

The package cpk provides simplified clinical pharmacokinetic functions for dose regimen design and modification at the point-of-care. Currently, the following functions are available: (1) ttc.fn for target therapeutic concentration, (2) dr.fn for dose rate, (3) di.fn for dosing interval, (4) dm.fn for maintenance dose, (5) bc.ttc.fn for back calculation, (6) ar.fn for accumulation ratio, (7) dpo.fn for orally administered dose, (8) cmax.fn for peak concentration, (9) css.fn for steady-state concentration, (10) cmin.fn for trough,(11) ct.fn for concentration-time predictions, (12) dlcmax.fn for calculating loading dose based on drug's maximum concentration, (13) dlar.fn for calculating loading dose based on drug's accumulation ratio, and (14) R0.fn for calculating drug infusion rate. Reference: Linares O, Linares A. Computational opioid prescribing: A novel application of clinical pharmacokinetics. J Pain Palliat Care Pharmacother 2011;25:125-135.

Author
Oscar A. Linares [aut, cre], David T. Daly [aut]
Date of publication
2013-12-26 08:12:11
Maintainer
Oscar A. Linares <OALinaresMD@gmail.com>
License
GPL-2
Version
1.3-1

View on CRAN

Man pages

ar.fn
Accumulation ratio function
bc.ttc.fn
Back-calculation function
cmax.fn
*cmax* function
cmin.fn
*cmin* function
cpk-package
Clinical Pharmacokinetics.
css.fn
*css* function
ct.fn
*ct* function
di.fn
*di* function
dlar.fn
Loading dose function
dlcmax.fn
Loading dose function
dm.fn
*dm* function
dpo.fn
*dpo* function
dr.fn
*dr* function
R0.fn
*R0* function
ttc.fn
*ttc* function

Files in this package

cpk
cpk/inst
cpk/inst/doc
cpk/inst/doc/vignettes
cpk/inst/doc/vignettes/walk-through.Rnw
cpk/inst/doc/vignettes/mancpk.Rnw
cpk/inst/doc/vignettes/mancpk.pdf
cpk/inst/doc/vignettes/walk-through.pdf
cpk/NAMESPACE
cpk/R
cpk/R/cpk.R
cpk/MD5
cpk/DESCRIPTION
cpk/man
cpk/man/bc.ttc.fn.Rd
cpk/man/dlar.fn.Rd
cpk/man/cpk-package.Rd
cpk/man/ttc.fn.Rd
cpk/man/di.fn.Rd
cpk/man/dr.fn.Rd
cpk/man/dpo.fn.Rd
cpk/man/dlcmax.fn.Rd
cpk/man/cmin.fn.Rd
cpk/man/ar.fn.Rd
cpk/man/R0.fn.Rd
cpk/man/cmax.fn.Rd
cpk/man/dm.fn.Rd
cpk/man/css.fn.Rd
cpk/man/ct.fn.Rd