css.fn: *css* function

In cpk: Clinical Pharmacokinetics

Description

Calculates css (steady-state) drug concentration in ng/mL, which is the same as ug/mL.

Usage

css.fn(f, dpo, di, cl, ar, wtkg)

Arguments

f	is bioavailability.
dpo	is oral dose administered in ug.
di	is the dosing interval in h.
cl	is the total clearance rate in L/kg/h.
ar	is stepwise accumulation ratio.
wtkg	is patient weight in kg.

Value

Returns css in mg/L and ug/L

Author(s)

Oscar A. Linares MD and David T. Daly JD/MBA.
Maintainer: Oscar A. Linares MD <[e-mail]>

References

See cpk-package help.

Examples

f <- 0.74; dpo <- 3440; di <- 4; cl <- 0.37; ar <-1.4; wtkg <- 86;
css <-css.fn(f, dpo, di, cl, ar, wtkg)

cpk documentation built on May 2, 2019, 3:42 a.m.