ctrdata
Retrieve and Analyze Clinical Trials Data from Public Registers

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README.md

README.md
In ctrdata: Retrieve and Analyze Clinical Trials Data from Public Registers

CRAN status codecov R-CMD-CHECK-win-macos-linux-duckdb-mongodb-sqlite-postgres

Main features • References • Installation • Overview • Databases • Data model • Example workflow • Analysis across registers • Tests • Acknowledgements • Future

ctrdata for aggregating and analysing clinical trials

The package ctrdata provides functions for retrieving (downloading), aggregating and analysing clinical trials using information (structured protocol and result data, as well as documents) from public registers. It can be used with the

The motivation is to investigate the design and conduct of trials of interest, to describe their trends and availability for patients and to facilitate using their detailed results for research and meta-analyses. ctrdata is a package for the R system, but other systems and tools can use the databases created with this package. This README was reviewed on 2025-06-07 for version 1.22.2.9000.

Main features

Remember to respect the registers’ terms and conditions (see ctrOpenSearchPagesInBrowser(copyright = TRUE)). Please cite this package in any publication as follows: “Ralf Herold (2025). ctrdata: Retrieve and Analyze Clinical Trials in Public Registers. R package version 1.22.2, https://cran.r-project.org/package=ctrdata”.

References

Package ctrdata has been used for unpublished works and these publications:

Installation

1. Install package ctrdata in R

Package ctrdata is on CRAN and on GitHub. Within R, use the following commands to install package ctrdata:

# Install CRAN version:
install.packages("ctrdata")

# Alternatively, install development version:
install.packages("devtools")
devtools::install_github("rfhb/ctrdata", build_vignettes = TRUE)

These commands also install the package’s dependencies (jsonlite, httr, curl, clipr, xml2, nodbi, stringi, tibble, lubridate, jqr, dplyr, zip, readr, digest, countrycode, htmlwidgets, stringdist and V8).

2. Script to automatically copy user’s query from web browser

Optional; works with all registers supported by ctrdata and is recommended for CTIS so that its URL in the web browser reflects the user’s parameters for querying this register.

In the web browser, install the Tampermonkey browser extension, click on “New user script” and then on “Tools”, enter into “Import from URL” this URL: https://raw.githubusercontent.com/rfhb/ctrdata/master/tools/ctrdataURLcopier.js and then click on “Install”.

The browser extension can be disabled and enabled by the user. When enabled, the URLs to all user’s queries in the registers are automatically copied to the clipboard and can be pasted into the queryterm = ... parameter of function ctrLoadQueryIntoDb().

Additionally, this script retrieves results for CTIS when opening search URLs such as https://euclinicaltrials.eu/ctis-public/search#searchCriteria={"status":[3,4]}. After changing the URL in the browser, a “Reload page” is needed to conduct the search and show results.

Overview of functions in ctrdata

The functions are listed in the approximate order of use in a user’s workflow (in bold, main functions). See also the package documentation overview.

| Function name | Function purpose | |----|----| | ctrOpenSearchPagesInBrowser() | Open search pages of registers or execute search in web browser | | ctrFindActiveSubstanceSynonyms() | Find synonyms and alternative names for an active substance | | ctrGenerateQueries() | 🔔 From simple user parameters, generates queries for each register to find trials of interest | | ctrGetQueryUrl() | Import from clipboard the URL of a search in one of the registers | | ctrLoadQueryIntoDb() | Retrieve (download) or update, and annotate, information on trials from a register and store in a collection in a database | | ctrShowOneTrial() | 🔔 Show full structure and all data of a trial, interactively select fields of interest for dbGetFieldsIntoDf() | | dbQueryHistory() | Show the history of queries that were downloaded into the collection | | dbFindIdsUniqueTrials() | Get the identifiers of de-duplicated trials in the collection | | dbFindFields() | Find names of variables (fields) in the collection | | dbGetFieldsIntoDf() | Create a data frame (or tibble) from trial records in the database with the specified fields | | dfTrials2Long() | Transform the data.frame from dbGetFieldsIntoDf() into a long name-value data.frame, including deeply nested fields | | dfName2Value() | From a long name-value data.frame, extract values for variables (fields) of interest (e.g., endpoints) | | dfMergeVariablesRelevel() | Merge variables into a new variable, optionally map values to a new set of levels |

Databases for use with ctrdata

Package ctrdata retrieves trial information and stores it in a database collection, which has to be given as a connection object to parameter con for several ctrdata functions. This connection object is created almost identically for the four database backends supported by ctrdata, as shown in the table. For a speed comparison, see the nodbi documentation.

Besides ctrdata functions below, such a connection object can be used with functions of other packages, such as nodbi (see last row in table) or, in case of MongoDB as database backend, mongolite (see vignettes).

| Purpose | Function call | |----|----| | Create SQLite database connection | dbc <- nodbi::src_sqlite(dbname = "name_of_my_database", collection = "name_of_my_collection") | | Create DuckDB database connection | dbc <- nodbi::src_duckdb(dbdir = "name_of_my_database", collection = "name_of_my_collection") | | Create MongoDB database connection | dbc <- nodbi::src_mongo(db = "name_of_my_database", collection = "name_of_my_collection") | | Create PostgreSQL database connection | dbc <- nodbi::src_postgres(dbname = "name_of_my_database"); dbc[["collection"]] <- "name_of_my_collection" | | Use connection with ctrdata functions | ctrdata::{ctrLoadQueryIntoDb, dbQueryHistory, dbFindIdsUniqueTrials, dbFindFields, dbGetFieldsIntoDf}(con = dbc, ...) | | Use connection with nodbi functions | e.g., nodbi::docdb_query(src = dbc, key = dbc$collection, ...) |

Data model of ctrdata

Package ctrdata uses the data models that are implicit in data as retrieved from the different registers. No mapping is provided for any register’s data model to a putative target data model. The reasons include that registers’ data models are continually evolving over time, that only few data fields have similar values and meaning between registers, and that the retrieved public data may not correspond to the registers’ internal data model. The structure of data for a specific trial can interactively be inspected and searched using function, see the section below.

Thus, the handling of data from different models of registers is to be done at the time of analysis. This approach allows a high level of flexibility, transparency and reproducibility. To support analyses, ctrdata (from version 1.21.0) provides functions that calculate concepts of clinical trials across registers, which are commonly used in analyses, such as start dates, age groups and statistical tests of results. See help(ctrdata-trial-concepts) and the section Analysis across trials in the example workflow below. For further analyses, see examples of function dfMergeVariablesRelevel() on how to align related fields from different registers for a joint analysis.

In any of the databases, one clinical trial is one document, corresponding to one row in a SQLite, PostgreSQL or DuckDB table, and to one document in a MongoDB collection. These NoSQL backends allow documents to have different structures, which is used here to accommodate the different models of data retrieved from the registers. Package ctrdata stores in every such document:

For visualising the data structure for a trial, see this vignette section.

Vignettes

Example workflow

The aim is to download protocol-related trial information and tabulate the trials’ status of conduct.

library(ctrdata)

help("ctrdata")

help("ctrdata-registers")

help("ctrdata-trial-concepts")

ctrOpenSearchPagesInBrowser()

# Please review and respect register copyrights:
ctrOpenSearchPagesInBrowser(copyright = TRUE)

q <- ctrGetQueryUrl()
# * Using clipboard content as register query URL: https://www.clinicaltrialsregister.eu/
# ctr-search/search?query=neuroblastoma&phase=phase-two&age=children
# * Found search query from EUCTR: query=neuroblastoma&phase=phase-two&age=children

q
#  query-term query-register
# 1 query=neuroblastoma&phase=phase-two&age=children          EUCTR

🔔 Queries in the trial registers can automatically copied to the clipboard (including for “CTIS”, where the URL otherwise does not show the user’s query) using the solution here.

For loading the trial information, first a database collection is specified, using nodbi (see above for how to specify PostgreSQL, RSQlite, DuckDB or MongoDB as backend, see section Databases):

# Connect to (or create) an SQLite database
# stored in a file on the local system:
db <- nodbi::src_sqlite(
  dbname = "database_name.sql",
  collection = "collection_name"
)

Then, the trial information is retrieved and loaded into the collection:

# Retrieve trials from public register:
ctrLoadQueryIntoDb(
  queryterm = q,
  euctrresults = TRUE,
  con = db
)
# * Checking trials in EUCTR...
# Retrieved overview, multiple records of 73 trial(s) from 4 page(s) to be downloaded (estimate: 9 MB)
# (1/3) Downloading trials...
# Note: register server cannot compress data, transfer takes longer (estimate: 90 s)
# Download status: 4 done; 0 in progress. Total size: 6.39 Mb (100%)... done!
# (2/3) Converting to NDJSON (estimate: 1 s)...
# (3/3) Importing records into database...
# = Imported or updated 270 records on 73 trial(s)
# * Checking results if available from EUCTR for 73 trials:
# (1/4) Downloading results...
# Download status: 73 done; 0 in progress. Total size: 22.57 Mb (100%)... done!
# Download status: 41 done; 0 in progress. Total size: 165.04 Kb (100%)... done!
# Download status: 41 done; 0 in progress. Total size: 165.04 Kb (100%)... done!
# - extracting results (. = data, F = file[s] and data, x = none):
# F F . . . . . . . F . . . F . . . F . . . . . F . . . . . . . F
# (2/4) Converting to NDJSON (estimate: 3 s)...
# (3/4) Importing results into database (may take some time)...
# (4/4) Results history: not retrieved (euctrresultshistory = FALSE)
# = Imported or updated results for 32 trials
# No history found in expected format.
# Updated history ("meta-info" in "some_collection_name")
# $n
# [1] 270

Under the hood, EUCTR plain text and XML files from EUCTR, CTGOV, ISRCTN are converted using Javascript via V8 in R into NDJSON, which is imported into the database collection.

The same parameters can be used to ask ctrdata to generate search queries that apply to each register, for opening the web interfaces and for loading the trial data into the collection:

# Generate queries for each register
queries <- ctrGenerateQueries(
  condition = "neuroblastoma",
  recruitment = "completed",
  phase = "phase 2",
  population = "P"
)

queries
# EUCTR 
# "https://www.clinicaltrialsregister.eu/ctr-search/search?query=neuroblastoma&phase=phase-two&age=children&age=adolescent&age=infant-and-toddler&age=newborn&age=preterm-new-born-infants&age=under-18&status=completed" 
# ISRCTN 
# "https://www.isrctn.com/search?&q=&filters=condition:neuroblastoma,phase:Phase II,ageRange:Child,trialStatus:completed,primaryStudyDesign:Interventional" 
# CTGOV2 
# "https://clinicaltrials.gov/search?cond=neuroblastoma&aggFilters=phase:2,ages:child,status:com,studyType:int" 
# CTGOV2expert 
# "https://clinicaltrials.gov/expert-search?term=AREA[ConditionSearch]\"neuroblastoma\" AND (AREA[Phase]\"PHASE2\") AND (AREA[StdAge]\"CHILD\") AND (AREA[OverallStatus]\"COMPLETED\") AND (AREA[StudyType]INTERVENTIONAL)" 
# CTIS 
# "https://euclinicaltrials.eu/ctis-public/search#searchCriteria={\"medicalCondition\":\"neuroblastoma\",\"trialPhaseCode\":[4],\"ageGroupCode\":[2],\"status\":[5,8]}" 

# Open queries in registers' web interfaces
sapply(queries, ctrOpenSearchPagesInBrowser)

# Load all queries into database collection
result <- lapply(queries, ctrLoadQueryIntoDb, con = db)

sapply(result, "[[", "n")
# EUCTR       ISRCTN       CTGOV2 CTGOV2expert         CTIS 
#   180            0          110          110            1

Tabulate the status of trials that are part of an agreed paediatric development program (paediatric investigation plan, PIP). ctrdata functions return a data.frame (or a tibble, if package tibble is loaded).

# Get all records that have values in the fields of interest:
result <- dbGetFieldsIntoDf(
  # Field of interest
  fields = c("a7_trial_is_part_of_a_paediatric_investigation_plan"),
  # Trial concepts calculated across registers
  calculate = c("f.statusRecruitment", "f.isUniqueTrial"),
  con = db
)
# Querying database (16 fields)...
# Searching for duplicate trials... 
# - Getting all trial identifiers (may take some time), 381 found in collection
# - Finding duplicates among registers' and sponsor ids...
# - 174 EUCTR _id were not preferred EU Member State record for 66 trials
# - Keeping 110 / 60 / 0 / 0 / 0 records from CTGOV2 / EUCTR / CTGOV / ISRCTN / CTIS
# = Returning keys (_id) of 170 records in collection "collection_name"

# Tabulate the clinical trial information of interest
with(
  result[result$.isUniqueTrial, ],
  table(
    .statusRecruitment,
    a7_trial_is_part_of_a_paediatric_investigation_plan
  )
)
#                   a7_trial_is_part_of_a_paediatric_investigation_plan
# .statusRecruitment FALSE TRUE
#        ongoing         2    3
#        completed      12    5
#        ended early     7    3
#        other           9    3

The new website and API introduced in July 2023 (https://www.clinicaltrials.gov/) is supported by ctrdata since mid-2023 and identified in ctrdata as CTGOV2.

On 2024-06-25, CTGOV has retired the classic website and API used by ctrdata since 2015. To support users, ctrdata automatically translates and redirects queries to the current website. This helps with automatically updating previously loaded queries (ctrLoadQueryIntoDb(querytoupdate = <n>)), manually migrating queries and reproducible work on clinical trials information. Going forward, users are recommended to change to use CTGOV2 queries.

As regards study data, important differences exist between field names and contents of information retrieved using CTGOV or CTGOV2; see the schema for study protocols in CTGOV, the schema for study results and the Study Data Structure for CTGOV2. For more details, call help("ctrdata-registers"). This is one of the reasons why ctrdata handles the situation as if these were two different registers and will continue to identify the current API as register = "CTGOV2", to support the analysis stage.

Note that loading trials with ctrdata overwrites the previous record with CTGOV2 data, whether the previous record was retrieved using CTGOV or CTGOV2 queries.

Example using a CTGOV query:

# CTGOV search query URL
q <- "https://classic.clinicaltrials.gov/ct2/results?cond=neuroblastoma&rslt=With&recrs=e&age=0&intr=Drug"

# Open old URL (CTGOV) in current website (CTGOV2):
ctrOpenSearchPagesInBrowser(q)
# * Appears specific for CTGOV Classic website
# Since 2024-06-25, the classic CTGOV servers are no longer available.
# Package ctrdata has translated the classic CTGOV query URL from this call
# of function ctrLoadQueryIntoDb(queryterm = ...) into a query URL that works
# with the current CTGOV2. This is printed below and is also part of the return
# value of this function, ctrLoadQueryIntoDb(...)$url. This URL can be used with
# ctrdata functions. Note that the fields and data schema of trials differ
# between CTGOV and CTGOV2.
#
# Replace this URL:
#
# https://classic.clinicaltrials.gov/ct2/results?cond=neuroblastoma&rslt=With&recrs=e&age=0&intr=Drug
#
# with this URL:
#
# https://clinicaltrials.gov/search?cond=neuroblastoma&intr=Drug&aggFilters=ages:child,results:with,status:com
#
# * Found search query from CTGOV2: cond=neuroblastoma&intr=Drug&aggFilters=ages:child,results:with,status:com

# Count trials:
ctrLoadQueryIntoDb(
  queryterm = q,
  con = db,
  only.count = TRUE
)
# $n
# [1] 71

Queries in the CTIS search interface can be automatically copied to the clipboard so that a user can paste them into queryterm, see here. Subsequent to the relaunch of CTIS on 2024-07-18, there are more than 8,700 trials publicly accessible in CTIS. See below for how to download documents from CTIS.

# See how many trials are in CTIS publicly accessible:
ctrLoadQueryIntoDb(
  queryterm = "",
  register = "CTIS",
  only.count = TRUE
)
# $n
# [1] 9181

For a given trial, function ctrShowOneTrial() enables the user to visualise the hiearchy of fields and contents in the user’s local web browser, to search for field names and field values, and to select and copy selected fields’ names for use with function dbGetFieldsIntoDf().

# This opens a local browser for user interaction.
# If the trial identifier (_id) is not found in the
# specified collection, it will be retrieved from the register.
ctrShowOneTrial(
  identifier = "2024-518931-12-00",
  con = db
)

Show cumulative start of trials over time. This uses the calculation of trial concepts as available since ctrdata version 1.21.0 🔔.

# use helper package
library(dplyr)
library(ggplot2)

df <- dbGetFieldsIntoDf(
  fields = "",
  calculate = c("f.statusRecruitment", "f.isUniqueTrial", "f.startDate"),
  con = db
)

df %>%
  filter(.isUniqueTrial) %>%
  ggplot() +
  stat_ecdf(aes(
    x = .startDate,
    colour = .statusRecruitment
  )) +
  labs(
    title = "Evolution over time of selected trials",
    subtitle = "Data from EUCTR, CTIS, ISRCTN, CTGOV2",
    x = "Date of start (proposed or realised)",
    y = "Cumulative proportion of trials",
    colour = "Current status",
    caption = Sys.Date()
  )

ggsave(
  filename = "man/figures/README-ctrdata_across_registers.png",
  width = 5, height = 3, units = "in"
)
Analysis across registers Analysis across registers

Analyse some simple result details, here from CTGOV2 (see this vignette for more examples):

# use helper package
library(ggplot2)

result <- dbGetFieldsIntoDf(
  calculate = c(
    "f.numSites",
    "f.sampleSize",
    "f.controlType",
    "f.numTestArmsSubstances"
  ),
  con = db
)

ggplot(data = result) +
  labs(
    title = "Selected trials",
    subtitle = "Patients with a neuroblastoma"
  ) +
  geom_point(
    mapping = aes(
      x = .numSites,
      y = .sampleSize,
      size = .numTestArmsSubstances,
      colour = .controlType
    )
  ) +
  scale_x_log10() +
  scale_y_log10() +
  labs(
    x = "Number of sites",
    y = "Total number of participants",
    colour = "Control",
    size = "# Treatments",
    caption = Sys.Date()
  )
ggsave(
  filename = "man/figures/README-ctrdata_results_neuroblastoma.png",
  width = 5, height = 3, units = "in"
)
Neuroblastoma trials Neuroblastoma trials 
### EUCTR document files can be downloaded when results are requested
# All files are downloaded and saved (documents.regexp is not used with EUCTR)
ctrLoadQueryIntoDb(
  queryterm = "query=cancer&age=under-18&phase=phase-one",
  register = "EUCTR",
  euctrresults = TRUE,
  documents.path = "./files-euctr/",
  con = db
)
# * Found search query from EUCTR: query=cancer&age=under-18&phase=phase-one
# * Checking trials in EUCTR...
# [...]
# = documents saved in './files-euctr'
# Updated history ("meta-info" in "some_collection_name")


### CTGOV files are downloaded, here corresponding to the default of
# documents.regexp = "prot|sample|statist|sap_|p1ar|p2ars|ctalett|lay|^[0-9]+ "
ctrLoadQueryIntoDb(
  queryterm = "cond=Neuroblastoma&type=Intr&recrs=e&phase=1&u_prot=Y&u_sap=Y&u_icf=Y",
  register = "CTGOV",
  documents.path = "./files-ctgov/",
  con = db
)
# * Checking for documents...
# - Getting links to documents
# - Downloading documents into 'documents.path' = ./files-ctgov/
# - Created directory ./files-ctgov
# - Applying 'documents.regexp' to 40 missing documents
# - Creating subfolder for each trial
# - Downloading 40 missing documents
# Download status: 40 done; 0 in progress. Total size: 110.75 Mb (100%)... done!
# = Newly saved 40 document(s) for 32 trial(s); 0 of such document(s) for 0 trial(s)
# already existed in ./files-ctgov


### CTGOV2 files are downloaded, using the default of documents.regexp
ctrLoadQueryIntoDb(
  queryterm = "https://clinicaltrials.gov/search?cond=neuroblastoma&aggFilters=phase:1,results:with",
  documents.path = "./files-ctgov2/",
  con = db
)
# * Checking for documents...
# - Getting links to documents
# - Downloading documents into 'documents.path' = ./files-ctgov2/
# - Created directory ./files-ctgov2
# - Creating subfolder for each trial
# - Applying 'documents.regexp' to 42 missing documents
# - Downloading 42 missing documents
# Download status: 42 done; 0 in progress. Total size: 92.57 Mb (100%)... done!
# = Newly saved 42 document(s) for 26 trial(s); 0 of such document(s) for 0
# trial(s) already existed in ./files-ctgov2


### ISRCTN files are downloaded, using the default of documents.regexp
ctrLoadQueryIntoDb(
  queryterm = "https://www.isrctn.com/search?q=alzheimer",
  documents.path = "./files-isrctn/",
  con = db
)
# * Found search query from ISRCTN: q=alzheimer
# [...]
# * Checking for documents...
# - Getting links to documents
# - Downloading documents into 'documents.path' = ./files-isrctn/
# - Created directory /Users/ralfherold/Daten/mak/r/emea/ctrdata/files-isrctn
# - Applying 'documents.regexp' to 52 missing documents
# - Creating subfolder for each trial
# - Downloading 32 missing documents
# Download status: 32 done; 0 in progress. Total size: 14.89 Mb (100%)... done!
# = Newly saved 26 document(s) for 15 trial(s); 0 of such document(s) for 0
# trial(s) already existed in ./files-isrctn


### CTIS files are downloaded, using the default of documents.regexp
ctrLoadQueryIntoDb(
  queryterm = paste0(
    "https://euclinicaltrials.eu/ctis-public/search#",
    'searchCriteria={"containAny":"cancer","status":[8]}'
  ),
  documents.path = "./files-ctis/",
  documents.regexp = "icf",
  con = db
)
# * Found search query from CTIS: searchCriteria={"containAny":"cancer"}
# [...]
# * Checking for documents: . . . . . . . . . . . . . . . . . . .
# - Downloading documents into 'documents.path' = ./files-ctis/
# - Applying 'documents.regexp' to 1114 missing documents
# - Creating subfolder for each trial
# - Downloading 512 missing documents (excluding 2 files with duplicate names
# for saving, e.g. /Users/ralfherold/Daten/mak/r/emea/ctrdata/files-ctis/2022-
# 500694-14-00/SbjctInfaICF - L1 SIS and ICF Prescreening ICF clean placeholder
# - 137297.PDF, /Users/ralfherold/Daten/mak/r/emea/ctrdata/files-ctis/2022-
# 500694-14-00/SbjctInfaICF - L1 SIS and ICF Pregnant Partner ICF clean -
# 137297.PDF)
# Download status: 510 done; 0 in progress. Total size: 377.27 Kb (100%)... done!
# Redirecting to CDN...
# Download status: 127 done; 0 in progress. Total size: 47.66 Mb (100%)... done!
# = Newly saved 510 document(s) for 35 trial(s); 0 of such document(s) for 0
# trial(s) already existed in ./files-ctis

Tests and coverage

See also https://app.codecov.io/gh/rfhb/ctrdata/tree/master/R

# 2025-05-17

tinytest::test_all()
# test_ctrdata_duckdb_ctgov2.R..   78 tests OK 46.4s
# test_ctrdata_function_activesubstance.R    4 tests OK 0.8s
# test_ctrdata_function_ctrgeneratequeries.R   14 tests OK 18ms
# test_ctrdata_function_params.R   25 tests OK 0.8s
# test_ctrdata_function_trial-concepts.R   80 tests OK 3.2s
# test_ctrdata_function_various.R   76 tests OK 3.7s
# test_ctrdata_postgres_ctgov2.R   50 tests OK 32.4s
# test_ctrdata_sqlite_ctgov.R...   46 tests OK 29.0s
# test_ctrdata_sqlite_ctgov2.R..   50 tests OK 25.9s
# test_ctrdata_sqlite_ctis.R....   87 tests OK 1.2s
# test_ctrdata_sqlite_euctr.R...  118 tests OK 47.7s
# test_ctrdata_sqlite_isrctn.R..   38 tests OK 12.0s
# test_euctr_error_sample.R.....    8 tests OK 0.2s
# All ok, 674 results (4m 36.8s)

covr::package_coverage(path = ".", type = "tests")
# ctrdata Coverage: 94.27%
# R/ctrShowOneTrial.R: 57.89%
# R/dbGetFieldsIntoDf.R: 80.14%
# R/zzz.R: 80.95%
# R/ctrRerunQuery.R: 86.23%
# R/ctrGetQueryUrl.R: 89.32%
# R/util_functions.R: 89.84%
# R/ctrLoadQueryIntoDbEuctr.R: 90.08%
# R/ctrFindActiveSubstanceSynonyms.R: 90.38%
# R/ctrLoadQueryIntoDbCtgov2.R: 92.68%
# R/ctrLoadQueryIntoDbIsrctn.R: 92.81%
# R/ctrLoadQueryIntoDbCtis.R: 95.34%
# R/dbFindFields.R: 95.88%
# R/f_primaryEndpointResults.R: 96.00%
# R/dfMergeVariablesRelevel.R: 96.55%
# R/ctrLoadQueryIntoDb.R: 96.86%
# R/ctrGenerateQueries.R: 97.32%
# R/ctrOpenSearchPagesInBrowser.R: 97.40%
# R/dbFindIdsUniqueTrials.R: 98.78%
# R/f_numTestArmsSubstances.R: 98.92%
# R/f_likelyPlatformTrial.R: 99.13%
# R/dbQueryHistory.R: 100.00%
# R/dfName2Value.R: 100.00%
# R/dfTrials2Long.R: 100.00%
# R/f_controlType.R: 100.00%
# R/f_isMedIntervTrial.R: 100.00%
# R/f_isUniqueTrial.R: 100.00%
# R/f_numSites.R: 100.00%
# R/f_primaryEndpointDescription.R: 100.00%
# R/f_resultsDate.R: 100.00%
# R/f_sampleSize.R: 100.00%
# R/f_sponsorType.R: 100.00%
# R/f_startDate.R: 100.00%
# R/f_statusRecruitment.R: 100.00%
# R/f_trialObjectives.R: 100.00%
# R/f_trialPhase.R: 100.00%
# R/f_trialPopulation.R: 100.00%
# R/f_trialTitle.R: 100.00%

Future features

Implemented:

Acknowledgements

Issues and notes

Trial records in databases

SQLite

Example JSON representation in SQLite Example JSON representation in SQLite

MongoDB

Example JSON representation in MongoDB Example JSON representation in MongoDB

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ctrdata documentation built on June 8, 2025, 10:45 a.m.

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