swrfM_design: Example of design matrix for the real SPM auditory dataset

Description Format References

Description

FMRI analysis requires the specification of the design matrix to be used in processing the general linear model. The design matrix defines the experimental design and the nature of hypothesis testing to be implemented. The design matrix has one row for each scan and one column for each effect or explanatory variable (regressor or stimulus function). The design matrix is used in fMRI analysis to specify the basis functions modeling the hemodynamic response function (HRF). It could be based on a single basis function or a set of functions. Two common basis function models are: (1) a single basis function is used for each explanatory variable; (2) a second time derivative basis functions is added to model (1), for each explanatory variable. The design matrix ‘swrfM_design.mat’ follows model (2) above for the auditory explanatory variable (2 regressors, excluding the intercept) . This design matrix goes with the file ‘swrfM_filtered_func_data.nii.gz’ used in the examples. The file ‘swrfM_filtered_func_data.nii.gz’ included in the package is a pre-processed file in gzipped NIFTI format of the auditory fMRI data set available from the SPM site (http://www.fil.ion.ucl.ac.uk/spm/). Note that cudaMultireg.slice includes an additional intercept variable for regression. Therefore the explanatory variable of interest for brain visualization purposes in Posterior Probability Mapping (PPM) is variable number 2 (referenced as vreg=2).

Format

The file ‘swrfM_design.mat’ used is a data frame with 84 observations on the following 2 explanatory variables: auditory, auditory temporal derivative. The file ‘swrfM_design.mat’ was generated by the FSL/FEAT tool. Similar procedures for generating design matrices for fMRI datasets are available in the SPM toolbox (http://www.fil.ion.ucl.ac.uk/spm/). The package cudaBayesreg, version 10+, uses the FSL format for the design matrices. The FSL-design format is simply a ASCII textfile with the fields /NumWaves, /NumPoints, /PPheights, and /Matrix. Therefore, it may easily edited if required.

References

FSL & FreeSurfer Course, Oxford Centre for Functional Magnetic Resonance Imaging of the Brain (FMRIB), University of Oxford. (www.fmrib.ox.ac.uk/fsl). SPM8 Manual, John Ashburner et. al., Functional Imaging Laboratory, Institute of Neurology, UCL, London, (http://www.fil.ion.ucl.ac.uk/spm/)


cudaBayesregData documentation built on May 29, 2017, 9:19 p.m.