cytometree: Automated Cytometry Gating and Annotation

Given the hypothesis of a bi-modal distribution of cells for each marker, the algorithm constructs a binary tree, the nodes of which are subpopulations of cells. At each node, observed cells and markers are modeled by both a family of normal distributions and a family of bi-modal normal mixture distributions. Splitting is done according to a normalized difference of AIC between the two families. Method is detailed in: Commenges, Alkhassim, Gottardo, Hejblum & Thiebaut (2018) <doi: 10.1002/cyto.a.23601>.

Package details

AuthorChariff Alkhassim [aut], Boris P Hejblum [cre, aut], Anthony Devaux [aut], Van Hung Huynh Tran [aut], Melany Durand [aut]
MaintainerBoris P Hejblum <boris.hejblum@u-bordeaux.fr>
LicenseLGPL-3 | file LICENSE
Version2.0.6
URL https://sistm.github.io/cytometree/ https://github.com/sistm/Cytometree/
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("cytometree")

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cytometree documentation built on Aug. 8, 2025, 7:17 p.m.