ccl4data | R Documentation |
The results of a closed chamber experiment to determine metabolic parameters for CCl4 (carbon tetrachloride) in rats.
data(ccl4data)
This data frame contains the following columns:
the time (in hours after starting the experiment).
initial chamber concentration (ppm).
this is a repeated measures design; this variable indicates which animal the observation pertains to.
chamber concentration at time
, in ppm.
Evans, et al. 1994 Applications of sensitivity analysis to a physiologically based pharmacokinetic model for carbon tetrachloride in rats. Toxicology and Applied Pharmacology 128: 36 – 44.
plot(ChamberConc ~ time, data = ccl4data, xlab = "Time (hours)",
xlim = range(c(0, ccl4data$time)),
ylab = "Chamber Concentration (ppm)", log = "y")
ccl4data.avg <- aggregate(ccl4data$ChamberConc,
by = ccl4data[c("time", "initconc")], mean)
points(x ~ time, data = ccl4data.avg, pch = 16)
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