dfcomb-package | R Documentation |
Phase I/II adaptive dose-finding design for combination studies where toxicity rates are supposed to increase with both agents.
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Marie-Karelle Riviere and Jacques-Henri Jourdan
Maintainer: Jacques-Henri Jourdan <jacques-henri.jourdan@normalesup.org>
Riviere MK, Yuan Y, Dubois F, Zohar S (2014). A Bayesian dose-finding design for drug combination clinical trials based on the logistic model. Pharm Stat, 13, 4:247-57.
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