matrix_effect: Assess matrix effects and matrix-matched calibrations

View source: R/matrix_effect.R

matrix_effectR Documentation

Assess matrix effects and matrix-matched calibrations


Calculate the matrix effect by comparing the slope of a solvent-based calibration curve with one or more matrix-matched calibration. The matrix effect is expressed as signal suppression/enhancement ratio.


matrix_effect(object, ...)

## S3 method for class 'calibration'
matrix_effect(object, ...)



an object of class 'calibration' obtained from analyzing standard solutions of different concentration (solvent calibration data).


additional objects of the same type obtained from matrix-matched calibration data.


Matrix effects or signal suppression/enhancement ratios should be evaluated during analytical method development to avoid over- or underestimation of sample concentrations. In addition, signal suppression/enhancement ratios may help to justify the validity of a regular solvent calibration as opposed to matrix-matched calibrations. This may be the case if matrix effects or signal suppression/enhancement ratios are close to measurement repeatability.


The magnitude of a matrix effect is estimated by subtracting the slope of a matrix-matched calibration from that of the solvent-based calibration. The difference is divided by the slope of the solvent-based calibration.


Julius Albert, Zacharias Steinmetz

See Also

Other calibration: calibration(), din32645, icp, neitzel2003, weight_select()


din <- calibration(Area ~ Conc, data = din32645)

m32645 <- din32645
m32645$Area <- din32645$Area * 1.5
matrix <- calibration(Area ~ Conc, data = m32645)

matrix_effect(din, matrix)

envalysis documentation built on Oct. 7, 2022, 5:06 p.m.