relative_risk: Calculate relative risks to be reported or plotted as dot...

In eudract: Creates Safety Results Summary in XML to Upload to EudraCT, or ClinicalTrials.gov

Calculate relative risks to be reported or plotted as dot plot

Description

Calculate relative risks to be reported or plotted as dot plot

Usage

relative_risk(
  safety,
  type = c("non_serious", "serious"),
  reference = safety$GROUP$title[1],
  size = 95
)

relative_risk_table(
  safety,
  type = c("non_serious", "serious"),
  reference = safety$GROUP$title[1],
  size = 95,
  digits = 3,
  valid_estimates = TRUE
)

order_filter(rel_risk, threshold = 10)

Arguments

safety	an object created by safety_summary
type	a choice of "non_serious" (default) or "serious" as to which type of AE to report on
reference	character vector nameing the refenrence arm for teh calculations. Defualts to the first row of the safety$GROUP.
size	a number between 0-100, giving the size of the confidence interval. Default is 95.
digits	integer giving the number of significant figures to report to. Default of 3.
valid_estimates	a logical, which determines if only terms with valid estimates of relative risk are included in the table. The alternative is to include terms with zeroes.
rel_risk	a relative risk object
threshold	a threshold on the percent scale, the max percentage for a term the incidence rate needs to exceed

Value

a data.frame that has the relative risk estimate and confidence intervals. No adjustment made to deal with zeroes.

A data frame that is suitable for printing to a report, giving relative risks

a revised relative risk object, with the terms concatenated with SOC if there are any duplicates, then ordered by relative risk, into a factor, and filtered to only those terms with an incidence rate above the threshold.

See Also

safety_summary dot_plot

Examples

safety_statistics <- safety_summary(safety,
           exposed=c("Experimental"=60,"Control"=67))
head( relative_risk(safety_statistics, type="serious") )
relative_risk_table(safety_statistics, type="serious")
rr <- relative_risk(safety_statistics)
rr2 <- order_filter(rr, threshold=2)
dot_plot(rr2)

eudract documentation built on Aug. 10, 2023, 1:10 a.m.