gsDesign: Group Sequential Design

Derives group sequential designs and describes their properties.

Author
Keaven Anderson
Date of publication
2016-02-01 22:09:41
Maintainer
Keaven Anderson <keaven_anderson@merck.com>
License
GPL (>= 2)
Version
3.0-1

View on CRAN

Man pages

binomial
3.2: Testing, Confidence Intervals, Sample Size and Power for...
eEvents
Expected number of events for a time-to-event study
gsBinomialExact
3.4: One-Sample Binomial Routines
gsbound
2.7: Boundary derivation - low level
gsBoundCP
2.5: Conditional Power at Interim Boundaries
gsBoundSummary
2.8: Bound Summary and Z-transformations
gsCP
2.4: Conditional and Predictive Power, Overall and...
gsDensity
2.6: Group sequential design interim density function
gsDesign
2.1: Design Derivation
gsDesign-package
1.0 Group Sequential Design
gsProbability
2.2: Boundary Crossing Probabilities
nNormal
Normal distribution sample size (2-sample)
normalGrid
3.1: Normal Density Grid
nSurv
Advanced time-to-event sample size calculation
nSurvival
3.4: Time-to-event sample size calculation (Lachin-Foulkes)
plot.gsDesign
2.3: Plots for group sequential designs
sfexp
4.3: Exponential Spending Function
sfHSD
4.1: Hwang-Shih-DeCani Spending Function
sfLDPocock
4.4: Lan-DeMets Spending function overview
sfLinear
4.6: Piecewise Linear and Step Function Spending Functions
sflogistic
4.7: Two-parameter Spending Function Families
sfpoints
4.5: Pointwise Spending Function
sfpower
4.2: Kim-DeMets (power) Spending Function
sfTDist
4.8: t-distribution Spending Function
sfTruncated
4.7a: Truncated, trimmed and gapped spending functions
spendingfunctions
4.0: Spending function overview
ssrCP
Sample size re-estimation based on conditional power
testutils
6.0 Utility functions to verify variable properties
Wang-Tsiatis-bounds
5.0: Wang-Tsiatis Bounds

Files in this package

gsDesign
gsDesign/inst
gsDesign/inst/NewTests
gsDesign/inst/NewTests/sfTruncatedTests.R
gsDesign/inst/NewTests/sfLinearTest.R
gsDesign/inst/NewTests/gsCPTests.R
gsDesign/inst/doc
gsDesign/inst/doc/gsSurvTemplateInstructions.pdf
gsDesign/inst/doc/gsSurvTemplate.rnw
gsDesign/inst/doc/gsSurvTemplate.pdf
gsDesign/inst/doc/gsDesignManual.pdf
gsDesign/inst/doc/gsSurvTemplateInstructions.rnw
gsDesign/inst/doc/gsDesignOverview.pdf
gsDesign/inst/unitTests
gsDesign/inst/unitTests/runit.gsCP-inputs.R
gsDesign/inst/unitTests/Makefile
gsDesign/inst/unitTests/runit.gsDesign-inputs.R
gsDesign/inst/unitTests/runit.gsbound1-inputs.R
gsDesign/inst/unitTests/runit.normalGrid-inputs.R
gsDesign/inst/unitTests/runit.gsDesign-stress.R
gsDesign/inst/unitTests/runit.sfnorm-inputs.R
gsDesign/inst/unitTests/runit.sflogistic-inputs.R
gsDesign/inst/unitTests/runit.ciBinomial-inputs.R
gsDesign/inst/unitTests/runit.nBinomial-inputs.R
gsDesign/inst/unitTests/runit.testBinomial-inputs.R
gsDesign/inst/unitTests/runit.gsbound-inputs.R
gsDesign/inst/unitTests/runit.simBinomial-inputs.R
gsDesign/inst/unitTests/runit.sfpower-inputs.R
gsDesign/inst/unitTests/runit.output.R
gsDesign/inst/unitTests/runit.sfcauchy-inputs.R
gsDesign/inst/unitTests/runit.sfHSD-inputs.R
gsDesign/inst/unitTests/runit.gsBoundCP-inputs.R
gsDesign/inst/unitTests/runit.testBinomial-stress.R
gsDesign/inst/unitTests/runit.gsProbability-inputs.R
gsDesign/inst/unitTests/doRUnit.R
gsDesign/inst/unitTests/runit.sflogistic.R
gsDesign/inst/unitTests/runit.plot.gsProbability-inputs.R
gsDesign/inst/unitTests/runit.sfexp-inputs.R
gsDesign/inst/unitTests/runit.plot.gsDesign-inputs.R
gsDesign/inst/unitTests/runit.sfTDist-inputs.R
gsDesign/src
gsDesign/src/gsbound1.c
gsDesign/src/h1.c
gsDesign/src/rprobrej.c
gsDesign/src/gsbound.c
gsDesign/src/stdnorpts.c
gsDesign/src/probpos.c
gsDesign/src/gsdensity.c
gsDesign/src/hupdate.c
gsDesign/src/gridpts.c
gsDesign/NAMESPACE
gsDesign/NEWS
gsDesign/R
gsDesign/R/nEvents.R
gsDesign/R/ssrCP.R
gsDesign/R/varBinomial.R
gsDesign/R/gsSimulate.R
gsDesign/R/gsCP.R
gsDesign/R/gsSurv.R
gsDesign/R/gsNormalGrid.R
gsDesign/R/gsSpending.R
gsDesign/R/gsqplot.R
gsDesign/R/gsMethods.R
gsDesign/R/nNormal.R
gsDesign/R/gsUtilities.R
gsDesign/R/gsBinomialExact.R
gsDesign/R/nBinomial1Sample.r
gsDesign/R/gsSurvival.R
gsDesign/R/gsWTPT.R
gsDesign/R/gsBinomial.R
gsDesign/R/xtable.R
gsDesign/R/gsDesign.R
gsDesign/vignettes
gsDesign/vignettes/gsSurvTemplate.rnw
gsDesign/vignettes/gsSurvTemplateInstructions.rnw
gsDesign/MD5
gsDesign/build
gsDesign/build/vignette.rds
gsDesign/DESCRIPTION
gsDesign/man
gsDesign/man/nNormal.Rd
gsDesign/man/gsBoundSummary.Rd
gsDesign/man/gsDesign.Rd
gsDesign/man/nSurv.Rd
gsDesign/man/eEvents.Rd
gsDesign/man/plot.gsDesign.Rd
gsDesign/man/gsbound.Rd
gsDesign/man/sfTruncated.Rd
gsDesign/man/sfpower.Rd
gsDesign/man/Wang-Tsiatis-bounds.Rd
gsDesign/man/gsDesign-package.Rd
gsDesign/man/sfHSD.Rd
gsDesign/man/gsBinomialExact.Rd
gsDesign/man/sfexp.Rd
gsDesign/man/sfLinear.Rd
gsDesign/man/sfLDPocock.Rd
gsDesign/man/sfpoints.Rd
gsDesign/man/testutils.Rd
gsDesign/man/ssrCP.Rd
gsDesign/man/sflogistic.Rd
gsDesign/man/gsDensity.Rd
gsDesign/man/gsProbability.Rd
gsDesign/man/normalGrid.Rd
gsDesign/man/nSurvival.Rd
gsDesign/man/gsBoundCP.Rd
gsDesign/man/binomial.Rd
gsDesign/man/gsCP.Rd
gsDesign/man/spendingfunctions.Rd
gsDesign/man/sfTDist.Rd