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In gsDesign: Group Sequential Design

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gsDesign documentation built on July 20, 2026, 9:06 a.m.

gsDesign index

Package overview README.md A cure model calendar-based design A gentle introduction to group sequential design Basic time-to-event group sequential design using gsSurv Binomial SPRT Binomial two arm trial design and analysis Conditional error spending functions Conditional power and conditional error Futility and harm bounds for overall survival monitoring Graphical testing for group sequential design gsDesign package overview Integer sample size and event counts Multiplicity graphs Multi-season studies for rare events Overview of survival endpoint design Power Computation for Group Sequential Survival Designs Reproducing SAS PROC SEQDESIGN survival designs in gsDesign Selective bound testing at interim analyses Spending function overview Two-sample normal sample size Vaccine efficacy trial design

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