op_fwer_cont: Provides operating characteristics of group sequential MAMS...

In gsMAMS: Group Sequential Designs of Multi-Arm Multi-Stage Trials

Provides operating characteristics of group sequential MAMS trial for continuous outcome under null hypothesis

Description

Computes FWER and other characteristics for group-sequential MAMS trial for continuous outcome.

Usage

op_fwer_cont(alpha, beta, p, frac, delta0, delta1, nsim, seed)

Arguments

alpha	numeric Type I error.
beta	numeric Type II error.
p	numeric Number of treatment arms.
frac	numeric vector of fractions for information time at each look.
delta0	numeric Standardized effect size in ineffective arm.
delta1	numeric Standardized effect size in effective arm.
nsim	numeric Number of simulations.
seed	numeric Random seed number.

Value

A list of FWER, stage-wise type I error, average sample size used per arm, stopping probability, probability of futility.

Examples

op_fwer_cont(alpha=0.05, beta=0.1, p=2, frac=c(0.5, 1), delta0=0.178, delta1=0.545, nsim=15,seed=1)

gsMAMS documentation built on May 29, 2024, 3:25 a.m.