op_power_cont: Provides operating characteristics of group sequential MAMS...

In gsMAMS: Group Sequential Designs of Multi-Arm Multi-Stage Trials

Provides operating characteristics of group sequential MAMS trial for continuous outcome

Description

Computes power and other characteristics for group-sequential MAMS trial for continuous outcome.

Usage

op_power_cont(alpha, beta, p, frac, delta0, delta1, nsim, seed)

Arguments

alpha	numeric Type I error.
beta	numeric Type II error.
p	numeric Number of treatment arms.
frac	numeric Vector of fractions for information time at each look.
delta0	numeric Standardized effect size in ineffective arm.
delta1	numeric Standardized effect size in effective arm.
nsim	numeric Number of simulations.
seed	numeric Random seed number.

Value

A list of power, stage-wise probability of success, average sample size used per arm, stopping probability, probability of futility.

Examples

op_power_cont(alpha = 0.05,
              beta = 0.1,
              p = 4,
              frac = c(1 / 5, 2 / 5, 3 / 5, 4 / 5, 1),
              delta0 = 0.178,
              delta1 = 0.545,
              nsim = 12,
              seed = 12)

gsMAMS documentation built on May 29, 2024, 3:25 a.m.