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Methods to extract information on pathways, genes and various single-nucleotid polymorphisms (SNPs) from online databases. It provides functions for data preparation and evaluation of genetic influence on a binary outcome using the logistic kernel machine test (LKMT). Three different kernel functions are offered to analyze genotype information in this variance component test: A linear kernel, a size-adjusted kernel and a network-based kernel).
Package details |
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Author | Juliane Manitz [aut, cre], Benjamin Hofner [aut], Stefanie Friedrichs [aut], Patricia Burger [aut], Ngoc Thuy Ha [aut], Saskia Freytag [ctb], Heike Bickeboeller [ctb] |
Maintainer | Juliane Manitz <r@manitz.org> |
License | GPL-2 |
Version | 1.4.2 |
URL | https://kangar00.manitz.org/ |
Package repository | View on CRAN |
Installation |
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