diabetes: Diabetes Data from Andrews and Herzberg

Description Format Details Author(s) References

Description

Data on 145 non-obese patients collected at the Stanford Clinical Reseach Center to investigate "the relationship between chemical subclinical and overt nonketotic diabetes. The three primary variables used in the analysis and presented [here] are glucose intolerance, insulin response to oral glucose, and insulin resistance."

From Andrews and Herzberg (1985) book called "Data". See reference.

Format

A data frame with 145 rows and 6 variables

RelativeWeight

The relative weight of the patient.

FastingPlasmaGlucose

The fasting plasma glucose level.

GlucoseArea

This is a measurement of the glucose intolerance as measured by the area under the straightline connecting glucose levels determined from blood samples drawn during a three hour glucose tolerance test following an oral administration of a glucose load.

InsulinArea

This is a measurement of the insulin response to oral glucose as measured by the area under the straightline connecting insulin levels, again determined from blood samples drawn during a three hour glucose tolerance test following an oral administration of a glucose load.

SSPG

The steady state plasma glucose (SSPG) determined after chemical suppression of endogenous insulin secretion. This is a measure of insulin resistance.

ClinClass

Clinical classification of each patient, by the contemporary (1979) medical criteria, into one of three groups: "Overt" diabetic, "Chemical" diabetic, or "Normal".

The row order of the values match the "Patient Number" given in the source table.

Details

This is a dataset from the "Data" book by Andrews and Herzberg (1985) Chapter 36, pp. 215-220 Table 36.1

A more complete description can be found there. An extract from the source follows.

The purpose of the data was to investigate

"the relationship between chemical subclinical and overt nonketotic diabetes in 145 non-obese adult subjects. The three primary variables used in the analysis and presented [here] are glucose intolerance, insulin response to oral glucose, and insulin resistance. The first two [of these] variables are the areas under the straightline connecting glucose and insulin levels, respectively, determined from blood samples drawn during a three hour glucose tolerance test following an oral administration of a glucose load. [These are variables GlucoseArea and InsulinArea, respectively.] Insulin resistance is measured by the steady state plasma glucose (SSPG) determined afterchemical suppression of endogenous insulin secretion. In addition, the relative weight and fasting plasma glucose were measured for each individual at the Stanford Clinical Reseach Center and are included [here]"

Each row of diabetes is a patient, and the row number is the "Patient Number" from Andrews and Herzberg.

Author(s)

R.W. Oldford

References

David F. Andrews and Agnes M. Herzberg (1985) "Data: A Collection of Problems from Many Fields for the Student and Research Worker", Springer, New York. <doi:10.1007/978-1-4612-5098-2>


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