Generalized Additive Model for Location, Scale and Shape (GAMLSS) with zero inflated beta (BEZI) family for analysis of microbiome relative abundance data (with various options for data transformation/normalization to address compositional effects) and random effects metaanalysis models for metaanalysis pooling estimates across microbiome studies are implemented. Random Forest model to predict microbiome age based on relative abundances of shared bacterial genera with the Bangladesh data (Subramanian et al 2014), comparison of multiple diversity indexes using linear/linear mixed effect models and some data display/visualization are also implemented. The reference paper is published by Ho NT, Li F, Wang S, Kuhn L (2019) <doi:10.1186/s1285901927442> .
Package details 


Author  Nhan Ho [aut, cre] 
Maintainer  Nhan Ho <[email protected]> 
License  GPL2 
Version  1.1 
URL  https://github.com/nhanhocu/metamicrobiomeR 
Package repository  View on CRAN 
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