mixtNB: DE Analysis of RNA-Seq Data by Mixtures of NB

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Differential expression analysis of RNA-Seq data when replicates under two conditions are available is performed. First, mixtures of Negative Binomial distributions are fitted on the data in order to estimate the dispersions, then the Wald test is computed.

Author
Elisabetta Bonafede, Cinzia Viroli
Date of publication
2015-05-02 14:11:25
Maintainer
Cinzia Viroli <cinzia.viroli@unibo.it>
License
GPL-3
Version
1.0

View on CRAN

Man pages

filter.em
Internal function that perform pre-filtering
fit.mixtNB
Fitting mixtures of Negative Binomials in RNA-Seq data
fun.a
Internal function for the Newton-Raphson step of the EM...
mixtNB-package
DE Analysis of RNA-Seq Data by Mixtures of Negative Binomials
wald.test
Wald test for performing DE analysis

Files in this package

mixtNB
mixtNB/NAMESPACE
mixtNB/R
mixtNB/R/fit.mixtNB.R
mixtNB/R/wald.test.R
mixtNB/MD5
mixtNB/DESCRIPTION
mixtNB/man
mixtNB/man/filter.em.Rd
mixtNB/man/fun.a.Rd
mixtNB/man/fit.mixtNB.Rd
mixtNB/man/wald.test.Rd
mixtNB/man/mixtNB-package.Rd