A method for performing differential expression analysis of RNA-Seq data when replicates under two conditions are available is implemented. First, mixtures of Negative Binomial distributions are fitted on the data in order to estimate the dispersions, then the Wald test is performed.
Authros: Elisabetta Bonafede, Cinzia Viroli
Maintainer: Cinzia Viroli <email@example.com>
E. Bonafede, F. Picard, S. Robin and C. Viroli (2015), Modelling overdispersion heterogeneity in differential expression analysis using mixtures, under revision.
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