simpopmlx: Population parameters simulation

In mlxR: Simulation of Longitudinal Data

Description

Draw population parameters using the covariance matrix of the estimates.

Usage

simpopmlx(
  n = 1,
  project = NULL,
  fim = "needed",
  parameter = NULL,
  corr = NULL,
  kw.max = 100
)

Arguments

n	the number of vectors of population parameters (default = 1),
project	a Monolix project, assuming that the Fisher information Matrix was estimated by Monolix.
fim	the Fisher Information Matrix estimated by Monolix. fim="sa", "lin" (default="sa")
parameter	a data frame with a column pop.param (no default), a column sd (no default), possibly a column trans (default ='N') and possibly columns lim.a (default=0) and lim.b (default=1). Only when project is not used.
corr	correlation matrix of the population parameters (default = identity). Only when project is not used.
kw.max	maximum number of trials for generating a positive definite covariance matrix (default = 100)

Details

See http://simulx.webpopix.org/mlxr/simpopmlx/ for more details.

Examples

## Not run: 
project.file <- 'monolixRuns/theophylline1_project.mlxtran'  #relative path
pop1 <- simpopmlx(n=3, project=project.file)

## End(Not run)

mlxR documentation built on Jan. 19, 2021, 5:06 p.m.