LPxt: Lethal Profile calculation

In morseTKTD: Bayesian Inference of TKTD Models

Lethal Profile calculation

Description

Predict the Lethal Profile factor leading to $x$ % of reduction in survival at a specific time $t$.

Generic method for LPxt, a function denoted LP(x,t) for x\

Usage

lpxt(fit, x, ...)

## S3 method for class 'SurvFit'
lpxt(
  fit,
  x = 0.5,
  t = NULL,
  display.exposure = NULL,
  interpolate_length = NULL,
  max.steps = 100,
  accuracy = 0.01,
  ...
)

## S3 method for class 'LPxt'
update(object, accuracy = 0.01, max.steps = 100, ...)

Arguments

fit	An object used to select a method
x	rate of individuals dying (e.g., 0.5 for LP_{50}, 0.1 for LP_{10}, ...).
...	Further arguments to be passed to generic methods
t	A number giving the time at which LP_{x} has to be estimated. If NULL, the latest time point of the experiment is used.
display.exposure	A vector of the exposure porfile
interpolate_length	of time point in the range of concentration between 0 and the maximal concentration. 100 by default. description.
max.steps	max steps to find the LPxt
accuracy	accuracy of the LPxt algorithm (stop when reaching the accuracy).
object	An object of class LPx

Value

returns an object of class LPxt

morseTKTD documentation built on June 8, 2025, 10:28 a.m.