mvmr_format: Organises the summary level data for use in the Bayesian MR...

In mrbayes: Bayesian Summary Data Models for Mendelian Randomization Studies

Description

Organises the summary level data for use in the Bayesian MR functions

Usage

mvmr_format(rsid, xbeta, ybeta, xse, yse)

Arguments

rsid	A vector of genetic variants used for analysis, if unspecified a vector is automatically generated.
xbeta	A matrix of multiple instrument-phenotypes associations.
ybeta	A numeric vector of the instrument-outcome associations.
xse	The matrix for corresponding standard errors of the instrument-phenotypes associations xbeta.
yse	The standard errors of the instrument-outcome associations ybeta.

Value

A formatted data frame for analysis of class mvmr_format.

Examples

data(dodata)
dat <- mvmr_format(rsid = dodata$rsid,
          xbeta = cbind(dodata$ldlcbeta,dodata$hdlcbeta,dodata$tgbeta),
          ybeta = dodata$chdbeta,
          xse = cbind(dodata$ldlcse,dodata$hdlcse,dodata$tgse),
          yse = dodata$chdse)
class(dat)

mrbayes documentation built on Oct. 2, 2021, 5:08 p.m.