mvmr_format: Organises the summary level data for use in the Bayesian MR...

In mrbayes: Bayesian Summary Data Models for Mendelian Randomization Studies

Organises the summary level data for use in the Bayesian MR functions

Description

Organises the summary level data for use in the Bayesian MR functions

Usage

mvmr_format(rsid, xbeta, ybeta, xse, yse)

Arguments

rsid	A vector of genetic variants used for analysis, if unspecified a vector is automatically generated.
xbeta	A matrix of multiple instrument-phenotypes associations.
ybeta	A numeric vector of the instrument-outcome associations.
xse	The matrix for corresponding standard errors of the instrument-phenotypes associations xbeta.
yse	The standard errors of the instrument-outcome associations ybeta.

Value

A formatted data frame for analysis of class mvmr_format.

Examples

data(dodata)
dat <- mvmr_format(
  rsid = dodata$rsid,
  xbeta = cbind(dodata$ldlcbeta,dodata$hdlcbeta,dodata$tgbeta),
  ybeta = dodata$chdbeta,
  xse = cbind(dodata$ldlcse,dodata$hdlcse,dodata$tgse),
  yse = dodata$chdse
)
class(dat)

mrbayes documentation built on Sept. 11, 2024, 6:45 p.m.