pval2locfdr: Strimmer et al.'s fdrtool-based local fdr

In mutoss: Unified Multiple Testing Procedures

Strimmer et al.'s fdrtool-based local fdr

Description

The function pval2locfdr takes a vector of p-values and estimates for each case the local fdr.

Usage

pval2locfdr(pValues, cutoff)

Arguments

pValues	pValues to be used.
cutoff	The local fdr cutoff for rejection. Hypotheses with local fdr smaller then cutoff will be rejected.

Value

A list containing:

locfdr	Numeric vector with local FDR values for each case
rejected	Logical vector indicating rejection/retention for each hypothesis when a cutoff is supplied.

Author(s)

JonathanRosenblatt

References

Strimmer, K. (2008). fdrtool: a versatile R package for estimating local and tail area-based false discovery rates. Bioinformatics 24: 1461-1462.
Efron B., Tibshirani R., Storey J. D. and Tusher, V. (2001). Empirical Bayes Analysis of a Microarray Experiment. Journal of the American Statistical Association 96(456):1151-1160.

Examples

pvals<- runif(1000)^2
pval2locfdr(pvals)
pval2locfdr(pValues=pvals, cutoff=0.4)

mutoss documentation built on March 31, 2023, 8:46 p.m.