nmtest: One compartment test dataset showing NONMEM 7.4.3 output
In nlmixr2data: Nonlinear Mixed Effects Models in Population PK/PD, Data

nmtest

R Documentation

One compartment test dataset showing NONMEM 7.4.3 output

Description

This is a example dataset originally created to show how similar mrgsolve and NONMEM were (See ).

Usage

nmtest

Format

A data frame with 7,157 rows and 15 columns

id: NONMEM id
time: NONMEM time
cp: NONMEM cp output from 7.4.3
cmt: cmt specification 1=depot, 2=central
amt: Nonmem dose
evid: NONMEM Event ID
ii: Interdose Interval
ss: Steady state flag
addl: Individual Clearance
rate: Rate of the infusion
lagt: Lag time
bioav: Bioavailability
rat2: Modeled rate when mode == 1
dur2: Duration when mode == 2
mode: Mode = 0 is no modification, modeled rate when mode=1 and modeled duration when mode=2

Details

The original dataset was created by Kyle Baron and is composed of id<100 the id>100 are modifications by Matthew Fidler to benchmark steady state infusions with lag times and other uncommon features.

Note that rxode2/nlmixr2 will not always match these behaviors by default, we choose behaviors that we believe make sense. There are options to make rxode2/nlmixr2 behave more like NONMEM. However behaviors we believe are wrong we do not support.

Author(s)

Kyle Baron & Matthew Fidler

Other nlmixr2 datasets: Bolus_1CPTMM, Bolus_1CPT, Bolus_2CPTMM, Bolus_2CPT, Infusion_1CPTMM, Infusion_1CPT, Infusion_2CPTMM, Infusion_2CPT, Oral_1CPTMM, Oral_1CPT, Oral_2CPTMM, Oral_2CPT, Wang2007, mavoglurant, nimoData, pheno_sd, rats, theo_md, theo_sd, warfarin, wbcSim