profileFixed: Estimate the objective function values for a model while...

In nlmixr2extra: Nonlinear Mixed Effects Models in Population PK/PD, Extra Support Functions

Estimate the objective function values for a model while fixing defined parameter values

Description

Estimate the objective function values for a model while fixing defined parameter values

Usage

profileFixed(fitted, which, control = list())

profileFixedSingle(fitted, which)

Arguments

fitted	The fit model
which	A data.frame with column names of parameters to fix and values of the fitted value to fix (one row only).
control	A list passed to fixedControl() (currently unused)

Value

which with a column named OFV added with the objective function value of the fitted estimate fixing the parameters in the other columns

Functions

• profileFixedSingle(): Estimate the objective function value for a model while fixing a single set of defined parameter values (for use in parameter profiling)

Author(s)

Bill Denney (changed by Matt Fidler to take out R 4.1 specific code)

See Also

Other Profiling: fixedControl(), llpControl(), profile.nlmixr2FitCore(), profileLlp(), profileNlmixr2FitCoreRet()

Other Profiling: fixedControl(), llpControl(), profile.nlmixr2FitCore(), profileLlp(), profileNlmixr2FitCoreRet()

nlmixr2extra documentation built on April 12, 2025, 1:41 a.m.