noise: Estimation of Intrinsic and Extrinsic Noise from Single-Cell Data

Functions to calculate estimates of intrinsic and extrinsic noise from the two-reporter single-cell experiment, as in Elowitz, M. B., A. J. Levine, E. D. Siggia, and P. S. Swain (2002) Stochastic gene expression in a single cell. Science, 297, 1183-1186. Functions implement multiple estimators developed for unbiasedness or min Mean Squared Error (MSE) in Fu, A. Q. and Pachter, L. (2016). Estimating intrinsic and extrinsic noise from single-cell gene expression measurements. Statistical Applications in Genetics and Molecular Biology, 15(6), 447-471.

Getting started

Package details

AuthorAudrey Qiuyan Fu and Lior Pachter
MaintainerAudrey Q. Fu <audreyqyfu@gmail.com>
LicenseGPL (>= 2)
Version1.0.2
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("noise")

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noise documentation built on May 29, 2024, 2:08 a.m.