noise: Estimation of Intrinsic and Extrinsic Noise from Single-Cell Data
Version 1.0

Functions to calculate estimates of intrinsic and extrinsic noise from the two-reporter single-cell experiment, as in Elowitz, M. B., A. J. Levine, E. D. Siggia, and P. S. Swain (2002) Stochastic gene expression in a single cell. Science, 297, 1183-1186. Functions implement multiple estimators developed for unbiasedness or min Mean Squared Error (MSE) in Fu, A. Q. and Pachter, L. (2016). Estimating intrinsic and extrinsic noise from single-cell gene expression measurements. .

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AuthorAudrey Qiuyan Fu and Lior Pachter
Date of publication2016-07-29 00:45:54
MaintainerAudrey Q. Fu <audreyqyfu@gmail.com>
LicenseGPL (>= 2)
Version1.0
Package repositoryView on CRAN
InstallationInstall the latest version of this package by entering the following in R:
install.packages("noise")

Man pages

computeExtrinsicNoise: Compute estimates of the extrinsic noise.
computeExtrinsicNoiseKnownCor: Compute estimates of the extrinsic noise using a known...
computeIntrinsicNoise: Compute estimates of the intrinsic noise.
computeNoiseForSubset: Select a random subset of data for noise estimation.
elowitz_data: Expression of reporter genes in the D22 and M22 E. coli cells...
noise-package: Estimation of Intrinsic and Extrinsic Noise from Single-Cell...
simulateSC: Simulate single-cell expression levels of two reporters
yang_nl10: Expression of reporter genes in the NL010 E. coli cells from...

Functions

computeExtrinsicNoise Man page Source code
computeExtrinsicNoiseKnownCor Man page Source code
computeIntrinsicNoise Man page Source code
computeNoiseForSubset Man page Source code
elowitz_data Man page
noise Man page
noise-package Man page
simulateSC Man page Source code
yang_nl10 Man page

Files

NAMESPACE
data
data/yang_nl10.rda
data/elowitz_data.rda
R
R/computeExtrinsicNoiseKnownCor.R
R/simulateSC.R
R/computeIntrinsicNoise.R
R/computeExtrinsicNoise.R
R/computeNoiseForSubset.R
MD5
build
build/partial.rdb
DESCRIPTION
man
man/computeExtrinsicNoise.Rd
man/computeExtrinsicNoiseKnownCor.Rd
man/computeIntrinsicNoise.Rd
man/elowitz_data.Rd
man/yang_nl10.Rd
man/noise-package.Rd
man/computeNoiseForSubset.Rd
man/simulateSC.Rd
noise documentation built on May 29, 2017, 12:04 p.m.