Functions to calculate estimates of intrinsic and extrinsic noise from the two-reporter single-cell experiment, as in Elowitz, M. B., A. J. Levine, E. D. Siggia, and P. S. Swain (2002) Stochastic gene expression in a single cell. Science, 297, 1183-1186. Functions implement multiple estimators developed for unbiasedness or min Mean Squared Error (MSE) in Fu, A. Q. and Pachter, L. (2016). Estimating intrinsic and extrinsic noise from single-cell gene expression measurements. Statistical Applications in Genetics and Molecular Biology, 15(6), 447-471.
Package details |
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Author | Audrey Qiuyan Fu and Lior Pachter |
Maintainer | Audrey Q. Fu <audreyqyfu@gmail.com> |
License | GPL (>= 2) |
Version | 1.0.2 |
Package repository | View on CRAN |
Installation |
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