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Design and analysis of confirmatory adaptive clinical trials using the optimal conditional error framework according to Brannath and Bauer (2004) <doi:10.1111/j.0006-341X.2004.00221.x>. An extension to the optimal conditional error function using interim estimates as described in Brannath and Dreher (2024) <doi:10.48550/arXiv.2402.00814> and functions to ensure that the resulting conditional error function is non-increasing are also available.
Package details |
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Author | Morten Dreher [aut, cre], Werner Brannath [aut, cph] (ORCID: <https://orcid.org/0000-0002-8622-3904>), Cornelia Ursula Kunz [ctb] (ORCID: <https://orcid.org/0000-0002-8900-9401>), Johanna zur Verth [aut] |
Maintainer | Morten Dreher <morten.dreher@outlook.de> |
License | GPL (>= 3) |
Version | 1.0.0 |
URL | https://github.com/morten-dreher/optconerrf |
Package repository | View on CRAN |
Installation |
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