paramlink2: Parametric Linkage Analysis

Parametric linkage analysis of monogenic traits in medical pedigrees. Features include singlepoint analysis, multipoint analysis via 'MERLIN' (Abecasis et al. (2002) <doi:10.1038/ng786>), visualisation of log of the odds (LOD) scores and summaries of linkage peaks. Disease models may be specified to accommodate phenocopies, reduced penetrance and liability classes. 'paramlink2' is part of the 'ped suite' package ecosystem, presented in 'Pedigree Analysis in R' (Vigeland, 2021, ISBN:9780128244302).

Getting started

Package details

AuthorMagnus Dehli Vigeland [aut, cre] (<https://orcid.org/0000-0002-9134-4962>)
MaintainerMagnus Dehli Vigeland <m.d.vigeland@medisin.uio.no>
LicenseGPL-3
Version1.0.3
URL https://github.com/magnusdv/paramlink2
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("paramlink2")

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paramlink2 documentation built on May 5, 2021, 1:08 a.m.