paramlink2: Parametric Linkage Analysis

Parametric linkage analysis of monogenic traits in medical pedigrees. Features include singlepoint analysis, multipoint analysis via 'MERLIN' (Abecasis et al. (2002) <doi:10.1038/ng786>), visualisation of log of the odds (LOD) scores and summaries of linkage peaks. Disease models may be specified to accommodate phenocopies, reduced penetrance and liability classes. 'paramlink2' is part of the 'ped suite' package ecosystem, presented in 'Pedigree Analysis in R' (Vigeland, 2021, ISBN:9780128244302).

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Package details

AuthorMagnus Dehli Vigeland [aut, cre] (<>)
MaintainerMagnus Dehli Vigeland <>
Package repositoryView on CRAN
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paramlink2 documentation built on May 5, 2021, 1:08 a.m.