beer.exprs: Lung adenocarcinoma microarray expression data of Beer et al....

In pensim: Simulation of High-Dimensional Data and Parallelized Repeated Penalized Regression

Lung adenocarcinoma microarray expression data of Beer et al. (2002)

Description

Lung adenocarcinomas were profiled by Beer et al. (2002) using Affymetrix hu6800 microarrays. The data here were normalized from raw .CEL files by RMAExpress (v0.3). The expression matrix contains expression data for 86 patients with 7,129 probe sets.

Usage

data(beer.exprs)

Format

A data frame with 7129 probe sets (rows) for 86 patients (columns)

Source

Beer DG, Kardia SL, Huang C, Giordano TJ, Levin AM, Misek DE, Lin L, Chen G, Gharib TG, Thomas DG, Lizyness ML, Kuick R, Hayasaka S, Taylor JM, Iannettoni MD, Orringer MB, Hanash S: Gene-expression profiles predict survival of patients with lung adenocarcinoma. Nat Med 2002, 8:816-824.

References

Irizarry, R.A., et al. (2003) Summaries of Affymetrix GeneChip probe level data, Nucl. Acids Res., 31, e15+-e15+.

Examples

data(beer.exprs)
mysd <- apply(beer.exprs, 1, sd)

beer.subset <- as.matrix(beer.exprs[rank(-mysd) <= 100, ])  
heatmap(beer.subset)

pensim documentation built on Dec. 9, 2022, 1:10 a.m.