get_pkc: Calculating pKc values
In powerHaDeX: Efficient Simulation of HDX-MS Data and Tools for the Statistical Analysis
View source: R/exchange_rates.R
get_pkc R Documentation
Calculating pKc values
Description
calculates supplementary constants for aspartic acid (Asp),
glutamic acid (Glu) and histidine (His). Values for mentioned amino acids are
pH and temperature dependent, in contrary to the rest amino acids with fixed
values.
Usage
get_pkc(temp_kelvin, gas_constant, exchange = "HD")
Arguments
temp_kelvin
temperature reaction in Kelvins
gas_constant
gas constant (1/(dT * R) = 1.9858775)
exchange
type of exchange - "HD" for hydrogen to deuterium,
"DH" for deuterium to hydrogen (back-exchange). Default "HD".
Details
Depending on provided exchange direction tabular values of
exponents E_const are assigned. For Asp, Glu and His
the pKc constants are calculated based on the energies of activation
for given amino acid and the chosen exchange direction.
Value
The function returns a list of asp, glu and his
(pKc values corresponding to amino acids).
powerHaDeX documentation built on March 18, 2022, 7:40 p.m.
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View source: R/exchange_rates.R
| get_pkc | R Documentation |
Calculating pKc values
Description
calculates supplementary constants for aspartic acid (Asp), glutamic acid (Glu) and histidine (His). Values for mentioned amino acids are pH and temperature dependent, in contrary to the rest amino acids with fixed values.
Usage
get_pkc(temp_kelvin, gas_constant, exchange = "HD")
Arguments
temp_kelvin |
temperature reaction in Kelvins |
gas_constant |
gas constant (1/(dT * R) = 1.9858775) |
exchange |
type of exchange - "HD" for hydrogen to deuterium, "DH" for deuterium to hydrogen (back-exchange). Default "HD". |
Details
Depending on provided exchange direction tabular values of
exponents E_const are assigned. For Asp, Glu and His
the pKc constants are calculated based on the energies of activation
for given amino acid and the chosen exchange direction.
Value
The function returns a list of asp, glu and his
(pKc values corresponding to amino acids).
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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