ppiPre: Predict Protein-Protein Interactions Based on Functional and Topological Similarities

Computing similarities between proteins based on their GO annotation, KEGG annotation and PPI network topology. It integrates seven features (TCSS, IntelliGO, Wang, KEGG, Jaccard, RA and AA) to predict PPIs using an SVM classifier. Some internal functions to calculate GO semantic similarities are re-used from R package GOSemSim authored by Guangchuang Yu.

Package details

AuthorYue Deng, Rongjie Shao, Gang Wang and Yuanjun Sun
MaintainerYue Deng <anfdeng@163.com>
Package repositoryView on CRAN
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ppiPre documentation built on May 30, 2017, 4:33 a.m.