set_clin | R Documentation |
This function allows user to specify the enrollment and drop-out rate, and the type of clinical cut-off Date. Both enrollment times and drop-out times follow piece-wise exponential distribution.
set_clin(gamma, e_itv, CCOD, CCOD_t, etaC, etaE, d_itv)
gamma |
A vector of rate of enrollment per unit of time |
e_itv |
A vector of duration of time periods for recruitment with rates specified in |
CCOD |
Type of analysis start time. Analysis starts at |
CCOD_t |
Time difference between analysis start and first patient's enrollment if |
etaC |
A vector for dropout rate per unit time for control arm |
etaE |
A vector for dropout rate per unit time for experimental arm. If left |
d_itv |
A vector of duration of time periods for dropping out the study with rates specified in |
A .clinClass
class containing information on enrollment time, drop-out pattern and analysis start time
# set the operational parameter values for the trial # analysis starts at64 time units after first patient in set_clin(gamma = 10, e_itv = 4, etaC = 0.003, CCOD = "fixed-first", CCOD_t = 64) # analysis starts at 12 time units after last patient in set_clin(gamma = 2, e_itv = 18, etaC = 0.005, CCOD = "fixed-last", CCOD_t = 12)
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