confint.predictCSC: Confidence Intervals and Confidence Bands for the Predicted...

In riskRegression: Risk Regression Models and Prediction Scores for Survival Analysis with Competing Risks

Confidence Intervals and Confidence Bands for the Predicted Absolute Risk (Cumulative Incidence Function)

Description

Confidence intervals and confidence Bands for the predicted absolute risk (cumulative incidence function).

Usage

## S3 method for class 'predictCSC'
confint(
  object,
  parm = NULL,
  level = 0.95,
  n.sim = 10000,
  absRisk.transform = "loglog",
  seed = NA,
  ...
)

Arguments

object	A predictCSC object, i.e. output of the predictCSC function.
parm	not used. For compatibility with the generic method.
level	[numeric, 0-1] Level of confidence.
n.sim	[integer, >0] the number of simulations used to compute the quantiles for the confidence bands.
absRisk.transform	[character] the transformation used to improve coverage of the confidence intervals for the predicted absolute risk in small samples. Can be "none", "log", "loglog", "cloglog".
seed	[integer, >0] seed number set before performing simulations for the confidence bands. If not given or NA no seed is set.
...	not used.

Details

The confidence bands and confidence intervals are automatically restricted to the interval [0;1].

Author(s)

Brice Ozenne

Examples

library(survival)
library(prodlim)
#### generate data ####
set.seed(10)
d <- sampleData(100) 

#### estimate a stratified CSC model ###
fit <- CSC(Hist(time,event)~ X1 + strata(X2) + X6, data=d)

#### compute individual specific risks
fit.pred <- predict(fit, newdata=d[1:3], times=c(3,8), cause = 1,
                    se = TRUE, iid = TRUE, band = TRUE)
fit.pred

## check confidence intervals
newse <- fit.pred$absRisk.se/(-fit.pred$absRisk*log(fit.pred$absRisk))
cbind(lower = as.double(exp(-exp(log(-log(fit.pred$absRisk)) + 1.96 * newse))),
      upper = as.double(exp(-exp(log(-log(fit.pred$absRisk)) - 1.96 * newse)))
)

#### compute confidence intervals without transformation
confint(fit.pred, absRisk.transform = "none")
cbind(lower = as.double(fit.pred$absRisk - 1.96 * fit.pred$absRisk.se),
      upper = as.double(fit.pred$absRisk + 1.96 * fit.pred$absRisk.se)
)

riskRegression documentation built on Sept. 8, 2023, 6:12 p.m.