scint: Relative Renal Function by Scintigraphy

In sdlrm: Modified Skew Discrete Laplace Regression for Integer-Valued and Paired Discrete Data

Relative Renal Function by Scintigraphy

Description

Data from a study conducted by Domingues et al. (2006) to compare the renal function measurements of 111 patients with either 99mTc-DTPA or 99mTc-EC dynamic scintigraphies with that measured using 99mTc-DMSA static scintigraphy. The measurements reflect the percentage of total renal function in the left kidney and were obtained on a discrete scale.

Usage

data(scint)

Format

A data frame with 111 observations on the following 4 variables.

• static: measurements obtained by static scintigraphy.

• dynamic: measurements obtained by dynamic scintigraphy, which may have been performed with the radiopharmaceutical 99mTc-DTPA or 99mTc-EC.

• difference: the difference between the renal functions measured using dynamic and static scintigraphies, that is, dynamic - static.

• agent: a factor with the radiopharmaceutical used in the dynamic scintigraphy, with levels "DTPA" and "EC".

• age: the patient age, in years.

• sex: a factor with the patient gender, with levels "F" and "M".

Details

Renal scintigraphy is a diagnostic imaging method of nuclear medicine used to measure kidney function. It is divided between static and dynamic, which differ in the procedure and the technical evaluation of the results. There are different radiopharmaceuticals used in the exam. For instance, static renal scintigraphies can use the technetium-99m dimercaptosuccinic acid (99mTc-DMSA), while dynamic scintigraphies can use the technetium-99m diethylenetriamine pentaacetic acid (99mTc-DTPA) or the technetium-99m ethylenedicysteine (99mTc-EC). The static renal agent 99mTc-DMSA is considered the most reliable method for measuring relative renal function (Kawashima et al., 1998; Martínez et al., 2002). However, this agent has drawbacks, such as relatively higher radiation dose (Kibar et al., 2003). Its comparison with different radiopharmaceuticals used in dynamic scintigraphy is of interest in the medical literature.

References

Domingues, F., Fujikawa, G., Decker, H., Alonso, G., Pereira, J., and Duarte, P. (2006). Comparison of relative renal function measured with either 99mTc-DTPA or 99mTc-EC dynamic scintigraphies with that measured with 99mTc-DMSA static scintigraphy. International Brazilian Journal of Urology, 32, 405—409.

Kibar, M., Yapar, Z., Noyan, A., and Anarat, A. (2003). Technetium-99m-N, N-ethylenedicysteine and Tc-99m DMSA scintigraphy in the evaluation of renal parenchymal abnormalities in children. Annals of Nuclear Medicine, 17, 219—225.

Kawashima, A., Sandler, C. M., and Goldman, S. M. (1998). Current roles and controversies in the imaging evaluation of acute renal infection. World Journal of Urology, 16, 9—17.

Martínez, M., JM, G. D., FJ, D. V., et al. (2002). Comparative study of differential renal function by DMSA and MAG-3 in congenital unilateral uropathies. Cirugía Pediátrica, 15, 118—121.

sdlrm documentation built on April 12, 2025, 1:15 a.m.