seqgendiff: RNA-Seq Generation/Modification for Simulation

Generates/modifies RNA-seq data for use in simulations. We provide a suite of functions that will add a known amount of signal to a real RNA-seq dataset. The advantage of using this approach over simulating under a theoretical distribution is that common/annoying aspects of the data are more preserved, giving a more realistic evaluation of your method. The main functions are select_counts(), thin_diff(), thin_lib(), thin_gene(), thin_2group(), thin_all(), and effective_cor(). See Gerard (2019) <doi:10.1101/758524> for details on the implemented methods.

Package details

AuthorDavid Gerard [aut, cre] (<https://orcid.org/0000-0001-9450-5023>)
MaintainerDavid Gerard <[email protected]>
LicenseGPL-3
Version1.1.1
URL https://github.com/dcgerard/seqgendiff
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("seqgendiff")

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seqgendiff documentation built on Sept. 10, 2019, 1:03 a.m.